Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | DAO | P14920 | 5/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.36 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20094779 | 0.86 | KMT2A (0.45) | DAOADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL15318252 | 0.78 | BAZ2B (0.50) | GAALMNAALDH1A1TDP1ERCC1 | |
| SCHEMBL15318227 | 0.78 | HSD17B10 (0.45) | GAADAOLMNAALDH1A1TDP1 | |
| SCHEMBL20094767 | 0.77 | DAO (0.49) | GAADAOALOX15LMNAALDH1A1 | |
| SCHEMBL161465 | 0.76 | ADORA3 (0.43) | GAAADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL20094517 | 0.75 | MAPT (0.49) | DAOALOX15ALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL24740414 | 0.75 | GRN (0.56) | GAAADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL20094573 | 0.73 | MMP13 (0.56) | ALOX15LMNARORCALDH1A1TDP1 | |
| SCHEMBL21180777 | 0.72 | SMN1; SMN2 (0.41) | GAAADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL20094768 | 0.70 | KMT2A (0.39) | GAADAOLMNAALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018075842-A1 | CONDENSED BENZODIAZEPINE DERIVATIVES AND CONJUGATES MADE THEREFROM | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-04-26 | — | — | WO | disclosed |