SCHEMBL2009691

SCHEMBL2009691

O=C(Cl)c1cccc(NC(=O)c2ccc(F)cc2)c1

nearest known ligand 0.76

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 8/20 0.76
KMT2A Q03164 8/20 0.76
KCNK3 O14649 3/20 0.74
KCNK9 Q9NPC2 2/20 0.74
RAB9A P51151 3/20 0.62
NPC1 O15118 2/20 0.62
HPGD P15428 1/20 0.62
MET P08581 1/20 0.60
PTGS2 P35354 1/20 0.60
MAPT P10636 2/20 0.59
CES1 P23141 1/20 0.59
SNCA P37840 1/20 0.58
LMNA P02545 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
POLB P06746 2/20 0.56
TDP1 Q9NUW8 1/20 0.56
HTR1F P30939 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2011998 0.88 KMT2A (0.72) MEN1KMT2AKCNK3KCNK9RAB9A
SCHEMBL1359652 0.87 KCNK3 (0.76) MEN1KMT2AKCNK3KCNK9RAB9A
SCHEMBL2358354 0.87 MEN1 (1.00) MEN1KMT2AKCNK3KCNK9RAB9A
SCHEMBL2012930 0.86 KCNK3 (0.67) MEN1KMT2AKCNK3KCNK9RAB9A
SCHEMBL1814173 0.86 KCNK3 (0.82) MEN1KMT2AKCNK3KCNK9RAB9A
SCHEMBL2103310 0.85 CES1 (0.60) MEN1KMT2AKCNK3KCNK9RAB9A
SCHEMBL2104422 0.85 RAB9A (0.69) MEN1KMT2AKCNK3RAB9ANPC1
Hydrochloric Acid SCHEMBL2107095 0.84 KCNK3 (0.79) MEN1KMT2AKCNK3KCNK9RAB9A
SCHEMBL2104420 0.84 KCNK3 (0.61) MEN1KMT2AKCNK3KCNK9RAB9A
SCHEMBL2106511 0.82 FADS1 (0.56) MEN1KMT2AKCNK3KCNK9RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230373947-A1 AMIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS INSECTICIDE MITSUI CHEMICALS, INC. (JP) 2023-11-23 US disclosed
US-11760742-B2 Amide derivatives, process for preparation thereof and use thereof as insecticide MITSUI CHEMICALS, INC. (JP) 2023-09-19 US disclosed
US-20210230135-A1 AMIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS INSECTICIDE MITSUI CHEMICALS, INC. (JP) 2021-07-29 US disclosed
US-10995081-B2 Amide derivatives, process for preparation thereof and use thereof as insecticide MITSUI CHEMICALS, INC. (JP) 2021-05-04 US disclosed
US-10435385-B2 Amide derivatives, process for preparation thereof and use thereof as insecticide MITSUI CHEMICALS, INC. (JP) 2019-10-08 US disclosed
US-20180134681-A1 AMIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS INSECTICIDE MITSUI CHEMICALS, INC. (JP) 2018-05-17 US disclosed
US-9920026-B2 Amide derivatives, process for preparation thereof and use thereof as insecticide MITSUI CHEMICALS, INC. (JP) 2018-03-20 US disclosed
EP-1714958-B9 AMIDE DERIVATIVES, PROCESS FOR PRODUCTION OF THE SAME, AND METHOD FOR APPLICATION THEREOF AS INSECTICIDE MITSUI CHEMICALS AGRO INC (JP) 2017-05-31 EP disclosed
EP-1714958-B1 AMIDE DERIVATIVES, PROCESS FOR PRODUCTION OF THE SAME, AND METHOD FOR APPLICATION THEREOF AS INSECTICIDE MITSUI CHEMICALS AGRO INC (JP) 2016-12-21 EP disclosed
US-20160002198-A1 AMIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS INSECTICIDE MITSUI CHEMICALS, INC. (JP) 2016-01-07 US disclosed
US-20090162453-A1 COMPOSITION FOR PREVENTING HARMFUL ORGANISMS MITSUI CHEMICALS, INC (JP) 2009-06-25 US disclosed
CN-101367748-A Amide derivatives, process for production of the same, and method for application thereof as insecticide MITSUI CHEMICALS INC (JP) 2009-02-18 CN disclosed
CN-101273009-A Insecticidal 3-acylaminobenzanilides BAYER CROPSCIENCE AG (DE) 2008-09-24 CN disclosed
EP-1938685-A1 INSECTICIDAL AND BACTERICIDAL COMPOSITION Mitsui Chemicals, Inc. (JP) 2008-07-02 EP disclosed
EP-1913815-A1 PEST CONTROL COMPOSITION Mitsui Chemicals, Inc. (JP) 2008-04-23 EP disclosed
EP-1912933-A1 INSECTICIDAL 3-ACYLAMINOBENZANILIDES Bayer CropScience AG (DE) 2008-04-23 EP disclosed
US-20070275980-A1 Amide Derivatives, Process For Preparation Thereof And Use Thereof As Insecticide MITSUI CHEMICALS, INC. (JP) 2007-11-29 US disclosed
CN-1926094-A Amide derivatives, process for their preparation and their use as pesticides MITSUI CHEMICALS INC (JP) 2007-03-07 CN disclosed
WO-2007017075-A1 INSECTICIDAL 3-ACYLAMINOBENZANILIDES BAYER CROPSCIENCE AG (DE) 2007-02-15 WO disclosed
EP-1714958-A1 AMIDE DERIVATIVES, PROCESS FOR PRODUCTION OF THE SAME, AND METHOD FOR APPLICATION THEREOF AS INSECTICIDE Mitsui Chemicals, Inc. (JP) 2006-10-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070275980-A1 Amide Derivatives, Process For Preparation Thereof And Use Thereof As Insecticide CYP1A1, CYP4B1, CYP2E1 MEN1 3376/4885KMT2A 1782/4885KCNK3 1494/4885
US-20180134681-A1 AMIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS INSECTICIDE CYP1A1, CYP4B1, CYP2E1 MEN1 3376/4885KMT2A 1782/4885KCNK3 1494/4885
US-20160002198-A1 AMIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS INSECTICIDE CYP1A1, CYP4B1, CYP2E1 MEN1 3376/4885KMT2A 1782/4885KCNK3 1494/4885
US-20230373947-A1 AMIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS INSECTICIDE DDT, CYP4B1, CYP2E1 MEN1 2759/4885KMT2A 565/4885KCNK3 3042/4885
US-20210230135-A1 AMIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS INSECTICIDE DDT, CYP4B1, CYP2E1 MEN1 2759/4885KMT2A 565/4885KCNK3 3042/4885
US-10435385-B2 Amide derivatives, process for preparation thereof and use thereof as insecticide DDT, CYP4B1, CYP2E1 MEN1 2759/4885KMT2A 565/4885KCNK3 3042/4885
US-20090162453-A1 COMPOSITION FOR PREVENTING HARMFUL ORGANISMS PRDX3, CYP1A1, GSTA1 MEN1 485/4885KMT2A 1594/4885KCNK3 2594/4885
US-11760742-B2 Amide derivatives, process for preparation thereof and use thereof as insecticide DDT, CYP4B1, CYP2E1 MEN1 2759/4885KMT2A 565/4885KCNK3 3042/4885
US-10995081-B2 Amide derivatives, process for preparation thereof and use thereof as insecticide DDT, CYP4B1, CYP2E1 MEN1 2759/4885KMT2A 565/4885KCNK3 3042/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.