Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | RORA | P35398 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | RORB | Q92753 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | MAT2A | P31153 | 3/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20096976 | 0.83 | KIF11 (0.43) | KIF11ALDH1A1PDE2AMAT2APDE10A | |
| SCHEMBL21311146 | 0.81 | NR1I2 (0.45) | ALDH1A1NPY5RHTR2AHTR2CMAPT | |
| SCHEMBL20097052 | 0.81 | KIF11 (0.64) | KIF11ALDH1A1NPY5RPDE2ARORA | |
| SCHEMBL21311350 | 0.80 | KIF11 (0.38) | KIF11ALDH1A1PDE2ARORARORC | |
| SCHEMBL20096984 | 0.77 | UTS2R (0.46) | ALDH1A1NPY5RMAPT | |
| SCHEMBL20097037 | 0.76 | KIF11 (0.51) | KIF11ALDH1A1NPY5RPDE2ARORA | |
| SCHEMBL24237299 | 0.75 | ALDH1A1 (0.41) | ALDH1A1HTR2AHTR2CMAPT | |
| SCHEMBL21311348 | 0.74 | ALDH1A1 (0.46) | KIF11ALDH1A1NPY5RPDE2ARORA | |
| SCHEMBL21304004 | 0.72 | ALDH1A1 (0.55) | KIF11ALDH1A1NPY5RPDE2ARORA | |
| SCHEMBL21304002 | 0.72 | NPY5R (0.59) | KIF11ALDH1A1NPY5RRORARORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190262371-A1 | METHODS AND COMPOSITION FOR THE TREATMENT OF RNA VIRAL INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2019-08-29 | — | — | US | disclosed |
| WO-2018075947-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF RNA VIRAL INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-04-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190262371-A1 | METHODS AND COMPOSITION FOR THE TREATMENT OF RNA VIRAL INFECTIONS | POLRMT, EIF2AK2, NSUN3 | KIF11 3214/4885ALDH1A1 3845/4885NPY5R 4867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.