SCHEMBL24237299

SCHEMBL24237299

Cc1cccc2c1c1c(C)cccc1n2C(C)C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.41
KMT2A Q03164 2/20 0.41
HPGD P15428 2/20 0.38
KDM4E B2RXH2 2/20 0.38
POLB P06746 1/20 0.37
HTR2A P28223 1/20 0.37
HTR2C P28335 1/20 0.37
TP53 P04637 1/20 0.36
DAO P14920 1/20 0.36
ALKBH5 Q6P6C2 1/20 0.35
FTO Q9C0B1 1/20 0.35
BCHE P06276 1/20 0.35
ACHE P22303 1/20 0.35
UTS2R Q9UKP6 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2A6 P11509 1/20 0.35
MAPT P10636 2/20 0.34
TSHR P16473 1/20 0.34
MAPK1 P28482 1/20 0.34
CASP1 P29466 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22336515 0.86 MAPT (0.41) ALDH1A1KMT2AHPGDKDM4EPOLB
SCHEMBL20096984 0.86 UTS2R (0.46) ALDH1A1KMT2AKDM4EPOLBALKBH5
SCHEMBL21311146 0.80 NR1I2 (0.45) ALDH1A1KMT2AKDM4EPOLBHTR2A
SCHEMBL18893250 0.77 ALDH1A1 (0.43) ALDH1A1KMT2AHPGDKDM4EPOLB
SCHEMBL20096980 0.75 KIF11 (0.46) ALDH1A1HTR2AHTR2CMAPT
SCHEMBL14188336 0.73 ALKBH5 (0.48) ALDH1A1KDM4EDAOALKBH5FTO
SCHEMBL25058938 0.71 CYP2A6 (0.38) ALDH1A1KDM4EHTR2AHTR2CDAO
SCHEMBL21076114 0.71 CDC25A (0.40) ALDH1A1HPGDKDM4EPOLBTP53
SCHEMBL21076112 0.71 AR (0.38) ALDH1A1HPGDKDM4EPOLBBCHE
SCHEMBL22336513 0.70 CDC25A (0.45) ALDH1A1KMT2AKDM4EPOLBALKBH5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11877506-B2 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2024-01-16 US disclosed
US-11877506-B2 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2024-01-16 US disclosed
US-20220037591-A1 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2022-02-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11877506-B2 Polycyclic aromatic compound F11, C1R, RNF31 ALDH1A1 2814/4885KMT2A 2002/4885HPGD 1870/4885
US-20220037591-A1 Polycyclic aromatic compound F11, C1R, RNF31 ALDH1A1 2814/4885KMT2A 2002/4885HPGD 1870/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.