SCHEMBL20097052

SCHEMBL20097052

CC(C)n1c2ccccc2c2ccc(C(F)(F)F)cc21

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 3/20 0.64
NPY5R Q15761 3/20 0.49
RORA P35398 1/20 0.46
RORC P51449 1/20 0.46
RORB Q92753 1/20 0.46
KMT2A Q03164 2/20 0.46
MEN1 O00255 1/20 0.46
ALDH1A1 P00352 1/20 0.46
BCHE P06276 1/20 0.43
ACHE P22303 1/20 0.43
MAPT P10636 2/20 0.43
TSHR P16473 1/20 0.43
MAPK1 P28482 1/20 0.43
CASP1 P29466 1/20 0.43
CASP7 P55210 1/20 0.43
ATM Q13315 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
MAT2A P31153 1/20 0.39
PDE2A O00408 1/20 0.38
GRM4 Q14833 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21304002 0.90 NPY5R (0.59) KIF11NPY5RRORARORCRORB
SCHEMBL20097037 0.85 KIF11 (0.51) KIF11NPY5RRORARORCRORB
SCHEMBL26996629 0.85 MEN1 (0.50) KIF11NPY5RRORARORCRORB
SCHEMBL21311147 0.85 KIF11 (0.57) KIF11NPY5RRORARORCRORB
SCHEMBL21311348 0.83 ALDH1A1 (0.46) KIF11NPY5RRORARORCRORB
SCHEMBL21304004 0.81 ALDH1A1 (0.55) KIF11NPY5RRORARORCRORB
SCHEMBL20096980 0.81 KIF11 (0.46) KIF11NPY5RRORARORCRORB
SCHEMBL150044 0.78 BCHE (0.59) NPY5RKMT2AMEN1ALDH1A1BCHE
SCHEMBL29780042 0.78 BCHE (0.59) NPY5RKMT2AMEN1ALDH1A1BCHE
SCHEMBL20097051 0.78 ATM (0.50) KIF11NPY5RRORARORCRORB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11638390-B2 Composition of matter for use in organic light-emitting diodes KYULUX, INC. (JP) 2023-04-25 US disclosed
US-10644249-B2 Composition of matter for use in organic light-emitting diodes KYULUX, INC. (JP) 2020-05-05 US disclosed
US-20200119287-A1 COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES KYULUX, INC. (JP) 2020-04-16 US disclosed
US-20190267554-A1 COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES Kyulux North America, Inc. 2019-08-29 US disclosed
US-20190262371-A1 METHODS AND COMPOSITION FOR THE TREATMENT OF RNA VIRAL INFECTIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2019-08-29 US disclosed
WO-2018075947-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF RNA VIRAL INFECTIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2018-04-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200119287-A1 COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES CRY2, CLTB, CYBA KIF11 3101/4885NPY5R 4097/4885RORA 900/4885
US-10644249-B2 Composition of matter for use in organic light-emitting diodes NDUFV3, SLCO1B3, CRY2 KIF11 3203/4885NPY5R 2745/4885RORA 697/4885
US-20190262371-A1 METHODS AND COMPOSITION FOR THE TREATMENT OF RNA VIRAL INFECTIONS POLRMT, EIF2AK2, NSUN3 KIF11 3214/4885NPY5R 4867/4885RORA 2229/4885
US-20190267554-A1 COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES NDUFV3, SLCO1B3, CRY2 KIF11 3203/4885NPY5R 2745/4885RORA 697/4885
US-11638390-B2 Composition of matter for use in organic light-emitting diodes CRY2, CLTB, CYBA KIF11 3101/4885NPY5R 4097/4885RORA 900/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.