Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNMT | Q14749 | 1/20 | 0.63 |
| ▸ | DOT1L | Q8TEK3 | 4/20 | 0.62 |
| ▸ | DNMT3B | Q9UBC3 | 2/20 | 0.62 |
| ▸ | PNMT | P11086 | 1/20 | 0.62 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.62 |
| ▸ | AHCY | P23526 | 7/20 | 0.62 |
| ▸ | NADK | O95544 | 1/20 | 0.62 |
| ▸ | PRMT7 | Q9NVM4 | 1/20 | 0.61 |
| ▸ | DPP4 | P27487 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.56 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.56 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.56 |
| ▸ | GAPDH | P04406 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.56 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.56 |
| ▸ | STAT6 | P42226 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20096991 | 0.89 | GNMT (0.66) | GNMTDOT1LDNMT3BPNMTDNMT1 | |
| SCHEMBL20097013 | 0.85 | ATM (0.59) | DOT1LAHCYNADKDPP4MEN1 | |
| SCHEMBL20097001 | 0.83 | DOT1L (0.61) | GNMTDOT1LDNMT3BPNMTDNMT1 | |
| SCHEMBL20096995 | 0.80 | DOT1L (0.66) | GNMTDOT1LDNMT3BPNMTDNMT1 | |
| SCHEMBL20096994 | 0.79 | DOT1L (0.80) | DOT1LDNMT3BPNMTDNMT1AHCY | |
| SCHEMBL21243035 | 0.79 | DOT1L (0.84) | DOT1LDNMT3BPNMTDNMT1AHCY | |
| SCHEMBL8943744 | 0.79 | DOT1L (0.82) | GNMTDOT1LDNMT3BPNMTDNMT1 | |
| SCHEMBL8943754 | 0.79 | DOT1L (0.82) | GNMTDOT1LDNMT3BPNMTDNMT1 | |
| SCHEMBL6908163 | 0.79 | AHCY (0.76) | DOT1LDNMT3BPNMTDNMT1AHCY | |
| SCHEMBL2115821 | 0.78 | AHCY (0.79) | DOT1LDNMT3BPNMTDNMT1AHCY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190262371-A1 | METHODS AND COMPOSITION FOR THE TREATMENT OF RNA VIRAL INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2019-08-29 | — | — | US | disclosed |
| WO-2018075947-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF RNA VIRAL INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-04-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190262371-A1 | METHODS AND COMPOSITION FOR THE TREATMENT OF RNA VIRAL INFECTIONS | POLRMT, EIF2AK2, NSUN3 | GNMT 1568/4885DOT1L 2274/4885DNMT3B 465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.