Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | F10 | P00742 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | TSPO | P30536 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28815311 | 0.66 | KDM4E (0.57) | KDM4ERAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL27431550 | 0.66 | PSEN1 (0.38) | KDM4EF10POLBMTNR1BALDH1A1 | |
| SCHEMBL12110619 | 0.65 | FABP4 (0.58) | KDM4EALDH1A1HPGDTSPO | |
| SCHEMBL699819 | 0.65 | GPR35 (0.53) | KDM4EF10POLBALDH1A1HPGD | |
| SCHEMBL19644452 | 0.64 | MAPT (0.45) | KDM4EPOLBRAB9AALDH1A1MEN1 | |
| SCHEMBL27354976 | 0.64 | TNF (0.51) | KDM4EF10RAB9AMEN1KMT2A | |
| SCHEMBL27343262 | 0.63 | KDM4E (0.54) | KDM4EPOLBALDH1A1L3MBTL1HTT | |
| SCHEMBL19013560 | 0.62 | NR1H2 (0.43) | L3MBTL1SLC9A1 | |
| SCHEMBL10165552 | 0.62 | HTR2A (0.51) | KDM4ERAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL22978577 | 0.62 | PLA2G10 (0.41) | KDM4EF10POLBMTNR1BRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018073753-A1 | FUSED TETRACYCLIC PYRIDONE COMPOUNDS AS ANTIVIRALS | NOVARTIS AG (CH) | 2018-04-26 | — | — | WO | disclosed |