Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.38 |
| ▸ | CASR | P41180 | 3/20 | 0.35 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28330130 | 0.80 | MIF (0.41) | MGLLNOTUMMCHR1POLBKCNH2 | |
| SCHEMBL31013537 | 0.76 | ALDH1A1 (0.46) | NOTUMLMNAL3MBTL1 | |
| SCHEMBL28111192 | 0.75 | CASR (0.37) | CASRMCHR1KCNH2 | |
| SCHEMBL10583896 | 0.73 | TUBB4A (0.38) | MGLLNOTUMLMNARECQLL3MBTL1 | |
| SCHEMBL84043 | 0.72 | PDE2A (0.53) | PTPN5PDE2ACYP2D6CYP2C9HIF1A | |
| Ammonia Solution, Strong SCHEMBL27642816 | 0.71 | PDE2A (0.52) | PTPN5PDE2ACYP2D6CYP2C9HIF1A | |
| SCHEMBL9259473 | 0.70 | GCGR (0.43) | MGLLNOTUMLMNAPOLBRECQL | |
| SCHEMBL28199860 | 0.69 | CA2 (0.35) | NOTUMMCHR1 | |
| SCHEMBL4631433 | 0.69 | ALDH1A1 (0.52) | MGLLNOTUMPOLBL3MBTL1MEN1 | |
| SCHEMBL14282014 | 0.68 | MGLL (0.57) | MGLLNOTUMLMNAPOLBRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9957281-B2 | Benzodiazepine derivatives as RSV inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2018-05-01 | — | — | US | disclosed |