Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 6/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21678054 | 0.89 | L3MBTL1 (0.65) | L3MBTL1LMNAALDH1A1KMT2ATDP1 | |
| SCHEMBL2860840 | 0.86 | L3MBTL1 (0.65) | L3MBTL1LMNAALDH1A1KMT2ATDP1 | |
| SCHEMBL25009812 | 0.82 | L3MBTL1 (0.76) | L3MBTL1LMNAALDH1A1KMT2ATDP1 | |
| SCHEMBL30556174 | 0.82 | L3MBTL1 (0.76) | L3MBTL1LMNAALDH1A1KMT2ATDP1 | |
| SCHEMBL11524658 | 0.82 | L3MBTL1 (0.59) | L3MBTL1LMNAALDH1A1KMT2ATDP1 | |
| SCHEMBL5353549 | 0.81 | L3MBTL1 (0.70) | L3MBTL1LMNAALDH1A1KMT2ATDP1 | |
| SCHEMBL24199837 | 0.80 | TSHR (0.49) | L3MBTL1LMNAALDH1A1TDP1MAPT | |
| SCHEMBL27603598 | 0.80 | L3MBTL1 (0.60) | L3MBTL1LMNAALDH1A1KMT2ATDP1 | |
| SCHEMBL382067 | 0.79 | L3MBTL1 (0.82) | L3MBTL1LMNAALDH1A1KMT2ATDP1 | |
| SCHEMBL4196772 | 0.79 | L3MBTL1 (0.68) | L3MBTL1LMNAALDH1A1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7632873-B2 | Cosmetic dermatological composition comprising at least one gradient copolymer, makeup comprising the cosmetic or dermatological composition and cosmetic method using the composition | L'OREAL S.A. (FR) | 2009-12-15 | — | — | US | claimed |
| EP-1684870-B1 | USE OF A COMPOSITIONALLY-GRADED COPOLYMER IN AN AEROSOL DEVICE COMPRISING TWO COMPARTMENTS, AND AEROSOL DEVICE COMPRISING SAID COPOLYMER AND A COMPRESSED GAS | OREAL (FR) | 2008-01-02 | — | — | EP | claimed |
| US-20070128127-A1 | Aerosol device containing a silicone, a gradient copolymer and a propellant essentially comprising dimethyl ether | L'OREAL (FR) | 2007-06-07 | — | — | US | claimed |
| US-20070086959-A1 | Use of a compositionally gradient copolymer in an aerosol device comprising two compartments, and aerosol device comprising said copolymer and a compressed gas | L'OREAL (FR) | 2007-04-19 | — | — | US | claimed |
| EP-1684870-A1 | USE OF A COMPOSITIONALLY-GRADED COPOLYMER IN AN AEROSOL DEVICE COMPRISING TWO COMPARTMENTS, AND AEROSOL DEVICE COMPRISING SAID COPOLYMER AND A COMPRESSED GAS | L'OREAL (FR) | 2006-08-02 | — | — | EP | claimed |
| EP-1656103-A2 | AEROSOL DEVICE CONTAINING A SILICONE, A GRADED COPOLYMER AND A PROPELLANT ESSENTIALLY COMPRISING DIMETHYLETHER | L'OREAL (FR) | 2006-05-17 | — | — | EP | claimed |
| US-20050255068-A9 | Cosmetic or dermatological composition comprising at least one gradient copolymer, makeup comprising the cosmetic or dermatological composition and cosmetic method using the composition | L'OREAL S.A. (FR) | 2005-11-17 | — | — | US | claimed |
| WO-2005020944-A1 | USE OF A COMPOSITIONALLY-GRADED COPOLYMER IN AN AEROSOL DEVICE COMPRISING TWO COMPARTMENTS, AND AEROSOL DEVICE COMPRISING SAID COPOLYMER AND A COMPRESSED GAS | L'OREAL (FR) | 2005-03-10 | — | — | WO | claimed |
| WO-2005020941-A2 | AEROSOL DEVICE CONTAINING A SILICONE, A GRADED COPOLYMER AND A PROPELLANT ESSENTIALLY COMPRISING DIMETHYLETHER | L'OREAL (FR) | 2005-03-10 | — | — | WO | claimed |
| US-20040202688-A1 | Nail varnish composition comprising at least one film-forming gradient copolymer and cosmetic process for making up or caring for the nails | L'OREAL S.A. (FR) | 2004-10-14 | — | — | US | claimed |
| US-20040191199-A1 | Cosmetic or dermatological composition comprising at least one gradient copolymer, makeup comprising the cosmetic or dermatological composition and cosmetic method using the composition | MOUGIN NATHALIE | 2004-09-30 | — | — | US | claimed |
| US-20040185017-A1 | Nail varnish composition comprising at least one film-forming gradient copolymer and cosmetic process for making up and/or caring for the nails | L'OREAL S.A. (FR) | 2004-09-23 | — | — | US | claimed |
| US-20040180019-A1 | Hair-cosmetic composition comprising at least one film-forming gradient copolymer, aerosol composition comprising the cosmetic composition and method for treating hair using the composition | L'OREAL S.A. (FR) | 2004-09-16 | — | — | US | claimed |
| EP-1444974-A2 | Hair care composition containing a filmbuilding copolmer with a gradient, aerosol composition and process for treating hair | L'OREAL (FR) | 2004-08-11 | — | — | EP | claimed |
| EP-1428496-A1 | Nail polish composition comprising a gradient polymer and the cosmetic process of treating or caring for nails | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| EP-1428495-A1 | Nail polish composition comprising a gradient polymer and the cosmetic process of treating or caring for nails | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| EP-1428493-A1 | Cosmetic or dermatological composition comprising a gradient copolymer and cosmetic process of make-up or care using this copolymer | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| US-7959906-B2 | Having specified strain at break, Young's modulus and/or instantaneous elastic recovery | L'OREAL S.A. (FR) | 2011-06-14 | — | — | US | disclosed |
| EP-1428496-A1 | Nail polish composition comprising a gradient polymer and the cosmetic process of treating or caring for nails | L'OREAL (FR) | 2004-06-16 | — | — | EP | disclosed |
| EP-1428495-A1 | Nail polish composition comprising a gradient polymer and the cosmetic process of treating or caring for nails | L'OREAL (FR) | 2004-06-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040191199-A1 | Cosmetic or dermatological composition comprising at least one gradient copolymer, makeup comprising the cosmetic or dermatological composition and cosmetic method using the composition | KRT18, POLR1C, CUTA | L3MBTL1 4868/4885LMNA 3662/4885ALDH1A1 1429/4885 |
| US-20040202688-A1 | Nail varnish composition comprising at least one film-forming gradient copolymer and cosmetic process for making up or caring for the nails | POLR1C, PIK3C3, NACA | L3MBTL1 3575/4885LMNA 3951/4885ALDH1A1 1819/4885 |
| US-20070086959-A1 | Use of a compositionally gradient copolymer in an aerosol device comprising two compartments, and aerosol device comprising said copolymer and a compressed gas | POLR1C, PLOD2, KRT18 | L3MBTL1 4582/4885LMNA 2432/4885ALDH1A1 2619/4885 |
| US-20070128127-A1 | Aerosol device containing a silicone, a gradient copolymer and a propellant essentially comprising dimethyl ether | POLR1C, SHH, DPM1 | L3MBTL1 4713/4885LMNA 2409/4885ALDH1A1 1948/4885 |
| US-20040185017-A1 | Nail varnish composition comprising at least one film-forming gradient copolymer and cosmetic process for making up and/or caring for the nails | POLR1C, PIK3C3, NACA | L3MBTL1 4209/4885LMNA 3391/4885ALDH1A1 1606/4885 |
| US-20050255068-A9 | Cosmetic or dermatological composition comprising at least one gradient copolymer, makeup comprising the cosmetic or dermatological composition and cosmetic method using the composition | KRT18, POLR1C, CUTA | L3MBTL1 4868/4885LMNA 3662/4885ALDH1A1 1429/4885 |
| US-20040180019-A1 | Hair-cosmetic composition comprising at least one film-forming gradient copolymer, aerosol composition comprising the cosmetic composition and method for treating hair using the composition | POLR1C, PFN1, POLL | L3MBTL1 4642/4885LMNA 544/4885ALDH1A1 1812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.