SCHEMBL20098204

SCHEMBL20098204

O=C(N[C@@H]1N=C(c2ccccc2)c2ccccc2NC1=O)O[C@H](CCN1CCOCC1)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CBLB Q13191 17/20 0.61
CCKAR P32238 4/20 0.53
CCKBR P32239 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29730517 1.00 CBLB (0.61) CBLBCCKARCCKBR
SCHEMBL20857014 1.00 CBLB (0.61) CBLBCCKARCCKBR
SCHEMBL29730541 1.00 CBLB (0.61) CBLBCCKARCCKBR
SCHEMBL20857012 1.00 CBLB (0.61) CBLBCCKARCCKBR
SCHEMBL20098202 1.00 CBLB (0.61) CBLBCCKARCCKBR
SCHEMBL3968844 0.81 CBLB (0.65) CBLBCCKARCCKBR
SCHEMBL24611856 0.81 CCKBR (0.53) CCKARCCKBR
SCHEMBL20867090 0.81 CCKBR (0.53) CCKARCCKBR
SCHEMBL29730441 0.79 CBLB (0.39) CBLB
SCHEMBL3823569 0.78 CBLB (0.66) CBLBCCKARCCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10881666-B2 Combination pharmaceutical agents as RSV inhibitors ENANTA PHARMACEUTICALS, INC. (US) 2021-01-05 US disclosed
US-10865215-B2 Benzodiazepine derivatives as RSV inhibitors ENANTA PHARMACEUTICALS, INC. (US) 2020-12-15 US disclosed
US-20200223867-A1 BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS ENANTA PHARM INC (US) 2020-07-16 US disclosed
US-10570153-B2 Benzodiazepine derivatives as RSV inhibitors ENANTA PHARMACEUTICALS, INC. (US) 2020-02-25 US disclosed
US-20190192535-A1 COMBINATION PHARMACEUTICAL AGENTS AS RSV INHIBITORS ENANTA PHARMACEUTICALS, INC. 2019-06-27 US disclosed
WO-2019067864-A1 COMBINATION PHARMACEUTICAL AGENTS AS RSV INHIBITORS ENANTA PHARMACEUTICALS, INC. (US) 2019-04-04 WO disclosed
US-9957281-B2 Benzodiazepine derivatives as RSV inhibitors ENANTA PHARMACEUTICALS, INC. (US) 2018-05-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10865215-B2 Benzodiazepine derivatives as RSV inhibitors GABRA5, GABRA1, GABBR2 CBLB 2850/4885CCKAR 989/4885CCKBR 509/4885
US-10881666-B2 Combination pharmaceutical agents as RSV inhibitors SERPINB1, FURIN, HIF1AN CBLB 4388/4885CCKAR 4257/4885CCKBR 3869/4885
US-10570153-B2 Benzodiazepine derivatives as RSV inhibitors GABRA5, GABRA1, GABBR2 CBLB 2850/4885CCKAR 989/4885CCKBR 509/4885
US-20200223867-A1 BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS GABRA5, GABRA1, GABBR2 CBLB 2850/4885CCKAR 989/4885CCKBR 509/4885
US-20190192535-A1 COMBINATION PHARMACEUTICAL AGENTS AS RSV INHIBITORS SERPINB1, FURIN, HIF1AN CBLB 4388/4885CCKAR 4257/4885CCKBR 3869/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.