SCHEMBL20101127

SCHEMBL20101127

Cc1cc(-c2ccc(N)cc2)cc(C)c1O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.64
CA2 P00918 1/20 0.64
ALDH1A1 P00352 6/20 0.50
CYP3A4 P08684 5/20 0.50
TDP1 Q9NUW8 4/20 0.50
TP53 P04637 2/20 0.50
TSHR P16473 3/20 0.46
CASP1 P29466 3/20 0.46
PDE10A Q9Y233 1/20 0.46
FYN P06241 3/20 0.45
CYP1A2 P05177 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
HSD17B10 Q99714 2/20 0.42
TAAR1 Q96RJ0 1/20 0.42
KDM4E B2RXH2 1/20 0.41
LMNA P02545 1/20 0.41
GAA P10253 1/20 0.41
MAPT P10636 1/20 0.41
ADORA2A P29274 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17060490 0.88 CA1 (0.82) CA1CA2ALDH1A1CYP3A4TDP1
SCHEMBL15445310 0.81 CA1 (0.70) CA1CA2ALDH1A1TDP1TP53
SCHEMBL17220670 0.81 CA1 (0.70) CA1CA2CYP1A2CYP2C9CYP2C19
SCHEMBL278774 0.81 CA1 (0.70) CA1CA2CYP1A2CYP2C9CYP2C19
SCHEMBL503537 0.81 CA1 (0.70) CA1CA2CYP1A2CYP2C9CYP2C19
SCHEMBL220910 0.80 CA1 (1.00) CA1CA2ALDH1A1CYP3A4TDP1
SCHEMBL22804025 0.80 CA1 (1.00) CA1CA2ALDH1A1CYP3A4TDP1
SCHEMBL8953908 0.79 CYP3A4 (0.52) CA1CA2ALDH1A1CYP3A4TDP1
SCHEMBL9579782 0.77 CA1 (0.64) CA1CA2ALDH1A1CYP3A4FYN
SCHEMBL8552828 0.77 CA1 (0.64) CA1CA2ALDH1A1CYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180119279-A1 PROCESS FOR PRODUCING FLEXIBLE ORGANIC-INORGANIC LAMINATES BASF COATINGS GMBH (DE) 2018-05-03 US disclosed
US-20180119279-A1 PROCESS FOR PRODUCING FLEXIBLE ORGANIC-INORGANIC LAMINATES BASF COATINGS GMBH (DE) 2018-05-03 US disclosed