Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.64 |
| ▸ | CA2 | P00918 | 1/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | BAD | Q92934 | 1/20 | 0.40 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.40 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21363128 | 0.90 | CA1 (0.50) | CA1CA2PTGS1PTGS2ALOX5 | |
| SCHEMBL17060490 | 0.88 | CA1 (0.82) | CA1CA2PTGS1PTGS2ALOX5 | |
| SCHEMBL3697459 | 0.82 | AKR1C2 (0.54) | CA1CA2KMT2AKDM4EALDH1A1 | |
| SCHEMBL15445310 | 0.81 | CA1 (0.70) | CA1CA2PTGS1PTGS2ALOX5 | |
| SCHEMBL503537 | 0.81 | CA1 (0.70) | CA1CA2ALOX5KMT2ACYP1A2 | |
| SCHEMBL278774 | 0.81 | CA1 (0.70) | CA1CA2ALOX5KMT2ACYP1A2 | |
| SCHEMBL17220670 | 0.81 | CA1 (0.70) | CA1CA2ALOX5KMT2ACYP1A2 | |
| SCHEMBL19387725 | 0.80 | MAOB (0.52) | CA1CA2PTGS1PTGS2 | |
| SCHEMBL3688994 | 0.80 | IKBKB (0.49) | CA1CA2PTGS1PTGS2ALOX5 | |
| SCHEMBL1513516 | 0.80 | HSD17B1 (0.60) | CYP2C19TNKS2ERCC1ERCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846986-A | Therapeutic phenoxyalkylazoles and phenoxyalkylazines | SANOFI (FR) | 1998-12-08 | — | — | US | disclosed |
| US-5721261-A | TREATING PICORNAVIRUS INFECTIONS | SANOFI PHARMACEUTICALS, INC. (US) | 1998-02-24 | — | — | US | disclosed |