Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18058766 | 0.89 | AKR1C3 (0.32) | — | |
| SCHEMBL20102793 | 0.86 | GSK3B (0.35) | NR3C2 | |
| SCHEMBL18040317 | 0.78 | MAPT (0.37) | — | |
| SCHEMBL18040314 | 0.78 | MAPT (0.37) | — | |
| SCHEMBL18058748 | 0.74 | GSK3B (0.39) | — | |
| SCHEMBL20694863 | 0.74 | GSK3B (0.39) | — | |
| SCHEMBL18058838 | 0.73 | MEN1 (0.36) | — | |
| SCHEMBL18058759 | 0.72 | S100A4 (0.34) | — | |
| SCHEMBL20709642 | 0.72 | MAPT (0.32) | — | |
| SCHEMBL1995413 | 0.71 | MAPT (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10385049-B2 | Dimer impurities of apixaban and method to remove them | F.I.S.—Fabbrica Italiana Sintetici S.p.A. (IT) | 2019-08-20 | — | — | US | disclosed |
| US-20180118737-A1 | DIMER IMPURITIES OF APIXABAN AND METHOD TO REMOVE THEM | F.I.S. - FABBRICA ITALIANA SINTETICI S.P.A. (IT) | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10385049-B2 | Dimer impurities of apixaban and method to remove them | F2, FGB, F8 | NR3C2 4402/4885 |
| US-20180118737-A1 | DIMER IMPURITIES OF APIXABAN AND METHOD TO REMOVE THEM | F2, FGB, F8 | NR3C2 4402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.