Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TACR2 | P21452 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13497712 | 0.89 | ALDH1A1 (0.51) | SRCALDH1A1L3MBTL1KDM4ELMNA | |
| SCHEMBL5351709 | 0.85 | SRC (0.53) | SRCALDH1A1L3MBTL1KDM4ELMNA | |
| SCHEMBL5144244 | 0.82 | SRC (0.47) | SRCALDH1A1L3MBTL1KDM4ELMNA | |
| SCHEMBL13858739 | 0.82 | ALDH1A1 (0.53) | SRCALDH1A1L3MBTL1KDM4EGAA | |
| SCHEMBL8612271 | 0.82 | SRC (0.50) | SRCALDH1A1L3MBTL1KDM4ELMNA | |
| SCHEMBL146679 | 0.80 | SRC (0.49) | SRCALDH1A1L3MBTL1MAPTHPGD | |
| SCHEMBL8035224 | 0.80 | THRA (0.51) | SRCALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL20887638 | 0.79 | SRC (0.45) | SRCALDH1A1L3MBTL1KDM4ELMNA | |
| SCHEMBL6850758 | 0.79 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1KDM4ELMNAMAPT | |
| SCHEMBL20271929 | 0.79 | SRC (0.47) | SRCALDH1A1L3MBTL1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8575208-B2 | Inhibitors of serine proteases | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2013-11-05 | — | — | US | disclosed |
| US-8575208-B2 | Inhibitors of serine proteases | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2013-11-05 | — | — | US | disclosed |
| US-8575208-B2 | Inhibitors of serine proteases | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2013-11-05 | — | — | US | disclosed |
| EP-2366704-B1 | Inhibitors of serine proteases | VERTEX PHARMA (US) | 2013-10-23 | — | — | EP | disclosed |
| EP-2366704-B1 | Inhibitors of serine proteases | VERTEX PHARMA (US) | 2013-10-23 | — | — | EP | disclosed |
| EP-2631238-A1 | Spirocyclic inhibitors of serine proteases for the treatment of hcv infections | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2013-08-28 | — | — | EP | disclosed |
| EP-2631238-A1 | Spirocyclic inhibitors of serine proteases for the treatment of hcv infections | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2013-08-28 | — | — | EP | disclosed |
| US-8440706-B2 | Inhibitors of serine proteases | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2013-05-14 | — | — | US | disclosed |
| US-8440706-B2 | Inhibitors of serine proteases | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2013-05-14 | — | — | US | disclosed |
| US-8440706-B2 | Inhibitors of serine proteases | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2013-05-14 | — | — | US | disclosed |
| EP-1370213-A4 | ASYMMETRIC BENZALDEHYDE ALDITOL DERIVATIVES, METHODS OF MAKING THEREOF, AND COMPOSITIONS AND ARTICLES CONTAINING SAME | MILLIKEN & CO (US) | 2005-01-26 | — | — | EP | disclosed |
| EP-1425342-A4 | NOVEL SYMMETRICAL SUBSTITUTED BENZALDEHYDE ALDITOL DERIVATIVES AND COMPOSITIONS AND ARTICLES CONTAINING SAME | MILLIKEN & CO (US) | 2005-01-05 | — | — | EP | disclosed |
| EP-1425342-A2 | NOVEL SYMMETRICAL SUBSTITUTED BENZALDEHYDE ALDITOL DERIVATIVES AND COMPOSITIONS AND ARTICLES CONTAINING SAME | Milliken & Company (US) | 2004-06-09 | — | — | EP | disclosed |
| EP-1370213-A2 | ASYMMETRIC BENZALDEHYDE ALDITOL DERIVATIVES, METHODS OF MAKING THEREOF, AND COMPOSITIONS AND ARTICLES CONTAINING SAME | Milliken & Company (US) | 2003-12-17 | — | — | EP | disclosed |
| US-6599964-B2 | Plastic additives useful as nucleating agents for improving optical properties/radiation transparency; for food or cosmetic containers and packaging | MILLIKEN & COMPANY | 2003-07-29 | — | — | US | disclosed |
| US-20030004238-A1 | Novel asymmetric substituted benzaldehyde alditol derivatives and compositions and articles containing same | MILLIKEN & COMPANY | 2003-01-02 | — | — | US | disclosed |
| US-6495620-B1 | PLASTIC ADDITIVES; NUCLEATING AGENTS; IMPROVING OPTICAL PROPERTIES SUCH AS TRANSPARENCY | MILLIKEN & COMPANY | 2002-12-17 | — | — | US | disclosed |
| US-20020183423-A1 | Novel symmetric substituted benzaldehyde alditol derivatives and compositions and articles containing same | MILLIKEN & COMPANY | 2002-12-05 | — | — | US | disclosed |
| WO-2002077086-A2 | NOVEL SYMMETRICAL SUBSTITUTED BENZALDEHYDE ALDITOL DERIVATIVES AND COMPOSITIONS AND ARTICLES CONTAINING SAME | MILLIKEN & COMPANY (US) | 2002-10-03 | — | — | WO | disclosed |
| WO-2002076385-A2 | ASYMMETRIC BENZALDEHYDE ALDITOL DERIVATIVES, METHODS OF MAKING THEREOF, AND COMPOSITIONS AND ARTICLES CONTAINING SAME | MILLIKEN & COMPANY (US) | 2002-10-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020183423-A1 | Novel symmetric substituted benzaldehyde alditol derivatives and compositions and articles containing same | SORD, PDK1, DDT | SRC 4627/4885ALDH1A1 154/4885L3MBTL1 1362/4885 |
| US-20030004238-A1 | Novel asymmetric substituted benzaldehyde alditol derivatives and compositions and articles containing same | ADH1C, SORD, PCNA | SRC 4659/4885ALDH1A1 46/4885L3MBTL1 989/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.