Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29657530 | 1.00 | HSD17B10 (0.38) | HSD17B10CFTRPOLBDHODHKDM4E | |
| SCHEMBL29657416 | 0.85 | GRIA4 (0.42) | HSD17B10POLBDHODHKDM4EGAA | |
| SCHEMBL20104394 | 0.85 | GRIA4 (0.42) | HSD17B10POLBDHODHKDM4EGAA | |
| SCHEMBL24313993 | 0.84 | GRIA4 (0.36) | DHODHGAACYP2C9L3MBTL1GRIA4 | |
| SCHEMBL1547280 | 0.78 | TDP1 (0.53) | CFTRPOLBDHODHKDM4EGAA | |
| SCHEMBL29657413 | 0.78 | L3MBTL1 (0.35) | HSD17B10POLBKDM4EMAPTGAA | |
| SCHEMBL20104512 | 0.78 | L3MBTL1 (0.35) | HSD17B10POLBKDM4EMAPTGAA | |
| SCHEMBL29657373 | 0.76 | ALDH1A1 (0.41) | HSD17B10POLBKDM4EMAPTGAA | |
| SCHEMBL20104424 | 0.76 | ALDH1A1 (0.41) | HSD17B10POLBKDM4EMAPTGAA | |
| SCHEMBL2003727 | 0.75 | ALDH1A1 (0.48) | HSD17B10POLBDHODHKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114456164-B | Pesticidally active heterocyclic derivatives with sulphur and hydroxylamine substituents | 先正达参股股份有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-109890818-B | Pesticidally active heterocyclic derivatives with sulphur and hydroxylamine substituents | 先正达参股股份有限公司 | 2022-11-25 | — | — | CN | disclosed |
| CN-114456164-A | Pesticidally active heterocyclic derivatives with sulphur and hydroxylamine substituents | 先正达参股股份有限公司 | 2022-05-10 | — | — | CN | disclosed |
| EP-3585770-B1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2022-03-23 | — | — | EP | disclosed |
| EP-3532471-B1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR AND HYDROXYLAMINE SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-09-15 | — | — | EP | disclosed |
| EP-3532471-B1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR AND HYDROXYLAMINE SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-09-15 | — | — | EP | disclosed |
| US-20210053970-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR AND HYDROXYLAMINE SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-02-25 | — | — | US | disclosed |
| US-10889583-B2 | Pesticidally active heterocyclic derivatives with sulphur and hydroxylamine substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2021-01-12 | — | — | US | disclosed |
| US-20190352299-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR AND HYDROXYLAMINE SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-11-21 | — | — | US | disclosed |
| CN-109890818-A | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR AND HYDROXYLAMINE SUBSTITUENTS | 先正达参股股份有限公司 | 2019-06-14 | — | — | CN | disclosed |
| WO-2018077565-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR AND HYDROXYLAMINE SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-05-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210053970-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR AND HYDROXYLAMINE SUBSTITUENTS | DDT, SHMT1, ACHE | HSD17B10 830/4885CFTR 3402/4885POLB 4023/4885 |
| US-10889583-B2 | Pesticidally active heterocyclic derivatives with sulphur and hydroxylamine substituents | DDT, ACHE, PNMT | HSD17B10 927/4885CFTR 2985/4885POLB 4021/4885 |
| US-20190352299-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR AND HYDROXYLAMINE SUBSTITUENTS | DDT, ACHE, PNMT | HSD17B10 927/4885CFTR 2985/4885POLB 4021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.