Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29657402 | 1.00 | L3MBTL1 (0.36) | L3MBTL1ALDH1A1MAPTKDM4EHSD17B10 | |
| SCHEMBL31194346 | 0.82 | EGLN1 (0.38) | L3MBTL1ALDH1A1MAPTKDM4EHSD17B10 | |
| SCHEMBL22190421 | 0.78 | L3MBTL1 (0.41) | L3MBTL1ALDH1A1MAPTKDM4EHSD17B10 | |
| SCHEMBL20104512 | 0.78 | L3MBTL1 (0.35) | L3MBTL1ALDH1A1MAPTKDM4EHSD17B10 | |
| SCHEMBL29657413 | 0.78 | L3MBTL1 (0.35) | L3MBTL1ALDH1A1MAPTKDM4EHSD17B10 | |
| SCHEMBL17514084 | 0.77 | PKM (0.36) | ALDH1A1MAPTKDM4EHSD17B10CYP1A2 | |
| SCHEMBL29904942 | 0.77 | PKM (0.36) | ALDH1A1MAPTKDM4EHSD17B10CYP1A2 | |
| SCHEMBL17422583 | 0.77 | MAPT (0.41) | L3MBTL1ALDH1A1MAPTKDM4EHSD17B10 | |
| SCHEMBL17824481 | 0.77 | L3MBTL1 (0.40) | L3MBTL1ALDH1A1MAPTKDM4EHSD17B10 | |
| SCHEMBL30614499 | 0.77 | MAPT (0.41) | L3MBTL1ALDH1A1MAPTKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12421237-B2 | Pesticidally active heterocyclic derivatives with sulfur containing substituents | SYNGENTA CROP PROTECTION AG (CH) | 2025-09-23 | — | — | US | disclosed |
| EP-3802542-B1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFOXIMINE CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2025-05-28 | — | — | EP | disclosed |
| CN-119431377-A | Pesticidally active heterocyclic derivatives with sulfoximine containing substituents | 先正达农作物保护股份公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-112262140-B | Pesticidally active heterocyclic derivatives with sulfoximine containing substituents | 先正达农作物保护股份公司 | 2024-05-28 | — | — | CN | disclosed |
| EP-4342297-A2 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFOXIMINE CONTAINING SUBSTITUENTS | Syngenta Crop Protection AG (CH) | 2024-03-27 | — | — | EP | disclosed |
| CN-114456164-B | Pesticidally active heterocyclic derivatives with sulphur and hydroxylamine substituents | 先正达参股股份有限公司 | 2024-03-12 | — | — | CN | disclosed |
| US-20230382866-A1 | PROCESS FOR THE PREPARATION OF 5-(1-CYANOCYCLOPROPYL)-PYRIDINE-2-CARBOXYLIC ACID ESTERS AMIDES AND NITRILES | SYNGENTA CROP PROTECTION AG (CH) | 2023-11-30 | — | — | US | disclosed |
| US-20230382866-A1 | PROCESS FOR THE PREPARATION OF 5-(1-CYANOCYCLOPROPYL)-PYRIDINE-2-CARBOXYLIC ACID ESTERS AMIDES AND NITRILES | SYNGENTA CROP PROTECTION AG (CH) | 2023-11-30 | — | — | US | disclosed |
| CN-116804010-A | Pesticidally active heterocyclic derivatives with sulfur containing substituents | 先正达参股股份有限公司 | 2023-09-26 | — | — | CN | disclosed |
| CN-110312707-B | Pesticidally active heterocyclic derivatives with sulfur containing substituents | 先正达参股股份有限公司 | 2023-06-23 | — | — | CN | disclosed |
| US-10889583-B2 | Pesticidally active heterocyclic derivatives with sulphur and hydroxylamine substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2021-01-12 | — | — | US | disclosed |
| WO-2019234158-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFOXIMINE CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2019-12-12 | — | — | WO | disclosed |
| WO-2019234158-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFOXIMINE CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2019-12-12 | — | — | WO | disclosed |
| US-20190352299-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR AND HYDROXYLAMINE SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-11-21 | — | — | US | disclosed |
| EP-3554242-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | Syngenta Participations AG (CH) | 2019-10-23 | — | — | EP | disclosed |
| US-20190308982-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-10-10 | — | — | US | disclosed |
| US-20190308982-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-10-10 | — | — | US | disclosed |
| WO-2018108726-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-06-21 | — | — | WO | disclosed |
| WO-2018108726-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-06-21 | — | — | WO | disclosed |
| WO-2018077565-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR AND HYDROXYLAMINE SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-05-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12421237-B2 | Pesticidally active heterocyclic derivatives with sulfur containing substituents | DDT, ACHE, SQOR | L3MBTL1 1139/4885ALDH1A1 884/4885MAPT 233/4885 |
| US-20230382866-A1 | PROCESS FOR THE PREPARATION OF 5-(1-CYANOCYCLOPROPYL)-PYRIDINE-2-CARBOXYLIC ACID ESTERS AMIDES AND NITRILES | CPS1, CBR1, CYP4B1 | L3MBTL1 4808/4885ALDH1A1 126/4885MAPT 3768/4885 |
| US-10889583-B2 | Pesticidally active heterocyclic derivatives with sulphur and hydroxylamine substituents | DDT, ACHE, PNMT | L3MBTL1 1255/4885ALDH1A1 343/4885MAPT 1014/4885 |
| US-20190308982-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | DDT, ACHE, SQOR | L3MBTL1 1076/4885ALDH1A1 652/4885MAPT 485/4885 |
| US-20190352299-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR AND HYDROXYLAMINE SUBSTITUENTS | DDT, ACHE, PNMT | L3MBTL1 1255/4885ALDH1A1 343/4885MAPT 1014/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.