Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.36 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20113578 | 0.88 | KMT2A (0.54) | KMT2AMEN1FAAHMAPK1ALDH1A1 | |
| SCHEMBL2009659 | 0.86 | MEN1 (0.51) | KMT2AMEN1FAAHMAPK1ALDH1A1 | |
| SCHEMBL13396654 | 0.84 | FAAH (0.50) | KMT2AMEN1FAAHMAPK1ALDH1A1 | |
| SCHEMBL2011698 | 0.81 | MEN1 (0.49) | KMT2AMEN1FAAHMAPK1ALDH1A1 | |
| SCHEMBL16124647 | 0.80 | FAAH (0.36) | KMT2AMEN1FAAHMAPK1ASAH2 | |
| SCHEMBL13396604 | 0.80 | FAAH (0.38) | KMT2AMEN1FAAHMAPK1ALDH1A1 | |
| SCHEMBL13396623 | 0.79 | PLA2G2A (0.49) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL20104862 | 0.79 | HPGD (0.46) | FAAHSMN1; SMN2CYP2D6CYP2C19GAA | |
| SCHEMBL16124621 | 0.78 | CNR2 (0.37) | KMT2AALDH1A1ESR2DPP4PTGS2 | |
| SCHEMBL13396678 | 0.78 | ALDH1A1 (0.42) | KMT2AMEN1FAAHMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10280138-B2 | Nitric oxide donating derivatives of fluprostenol | NICOX S.A. (FR) | 2019-05-07 | — | — | US | disclosed |
| US-20180118677-A1 | NITRIC OXIDE DONATING DERIVATIVES OF FLUPROSTENOL | NICOX S.A. (FR) | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180118677-A1 | NITRIC OXIDE DONATING DERIVATIVES OF FLUPROSTENOL | PTGIS, NOS2, PTGIR | KMT2A 4013/4885MEN1 3031/4885FAAH 650/4885 |
| US-10280138-B2 | Nitric oxide donating derivatives of fluprostenol | PTGIS, NOS2, PTGIR | KMT2A 4013/4885MEN1 3031/4885FAAH 650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.