Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12925545 | 0.84 | DGAT1 (0.40) | DGAT1MAPTALDH1A1CYP19A1GAA | |
| SCHEMBL29909266 | 0.79 | POLB (0.40) | DGAT1ALDH1A1CYP19A1PIK3CD | |
| SCHEMBL77078 | 0.79 | POLB (0.40) | DGAT1ALDH1A1CYP19A1PIK3CD | |
| SCHEMBL17428946 | 0.78 | GRM4 (0.40) | DGAT1MAPTALDH1A1CYP19A1GRM4 | |
| SCHEMBL16374865 | 0.78 | ESR1 (0.36) | MAPTESR1ESR2 | |
| SCHEMBL19509459 | 0.78 | ESR1 (0.36) | CYP19A1ESR1ESR2 | |
| SCHEMBL21719135 | 0.77 | CNR2 (0.38) | DGAT1MAPTALDH1A1ESR1ESR2 | |
| SCHEMBL22778781 | 0.77 | CYP19A1 (0.32) | CYP19A1ESR1ESR2 | |
| SCHEMBL11913147 | 0.76 | ESR1 (0.35) | CYP19A1ESR1ESR2 | |
| SCHEMBL611752 | 0.76 | DGAT1 (0.37) | DGAT1MAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11330821-B2 | Herbicidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2022-05-17 | — | — | US | disclosed |
| US-20210238176-A1 | PESTICIDALLY-ACTIVE BICYCLIC HETEROAROMATIC COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2021-08-05 | — | — | US | disclosed |
| US-20180116219-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11330821-B2 | Herbicidal compounds | DDT, HPD, HDHD5 | DGAT1 725/4885MAPT 3760/4885ALDH1A1 258/4885 |
| US-20210238176-A1 | PESTICIDALLY-ACTIVE BICYCLIC HETEROAROMATIC COMPOUNDS | DDT, ACHE, CYP1B1 | DGAT1 2000/4885MAPT 326/4885ALDH1A1 659/4885 |
| US-20180116219-A1 | HERBICIDAL COMPOUNDS | DDT, HPD, HDHD5 | DGAT1 725/4885MAPT 3760/4885ALDH1A1 258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.