Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 3/20 | 0.34 |
| ▸ | CACNG8 | Q8WXS5 | 3/20 | 0.34 |
| ▸ | CACNG2 | Q9Y698 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20112881 | 0.90 | AHR (0.35) | — | |
| SCHEMBL20112979 | 0.88 | ROCK1 (0.32) | GRIA1CACNG8 | |
| SCHEMBL20112906 | 0.87 | LPL (0.31) | GRIA1CACNG8 | |
| SCHEMBL20112974 | 0.86 | CSF1R (0.30) | — | |
| SCHEMBL18189401 | 0.85 | GRIA1 (0.38) | GRIA1CACNG8CACNG2 | |
| SCHEMBL25826937 | 0.77 | ROCK1 (0.31) | — | |
| SCHEMBL21382167 | 0.76 | CYP11B1 (0.35) | — | |
| SCHEMBL18189549 | 0.74 | AHR (0.43) | GRIA1CACNG8CACNG2 | |
| SCHEMBL18189371 | 0.73 | LIPG (0.35) | — | |
| SCHEMBL15288616 | 0.71 | LIPG (0.40) | GRIA1CACNG8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018080917-A1 | FUSED BICYLIC PYRIDINE COMPOUNDS AND THEIR USE AS AMPA RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-03 | — | — | WO | disclosed |