Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20112979 | 0.89 | ROCK1 (0.32) | ROCK1 | |
| SCHEMBL15288616 | 0.84 | LIPG (0.40) | ROCK1 | |
| SCHEMBL20106736 | 0.77 | GRIA1 (0.34) | — | |
| SCHEMBL20112881 | 0.76 | AHR (0.35) | — | |
| SCHEMBL21493489 | 0.75 | KIF11 (0.39) | ROCK1 | |
| SCHEMBL20112974 | 0.74 | CSF1R (0.30) | — | |
| SCHEMBL20112906 | 0.71 | LPL (0.31) | — | |
| SCHEMBL18189371 | 0.70 | LIPG (0.35) | ROCK1 | |
| SCHEMBL18189401 | 0.70 | GRIA1 (0.38) | — | |
| SCHEMBL18189549 | 0.69 | AHR (0.43) | ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023133375-A1 | MACROCYCLIC COMPOUNDS AND USE AS KINASE INHIBITORS | BLOSSOMHILL THERAPEUTICS, INC. (US) | 2023-07-13 | — | — | WO | disclosed |