Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | BRD2 | P25440 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.34 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.34 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5500966 | 0.76 | BRD4 (0.49) | RXRARXRBMAPTMEN1KMT2A | |
| SCHEMBL17402907 | 0.73 | CYP3A4 (0.45) | MAPTKMT2AHSD17B10POLBBRD4 | |
| SCHEMBL20108705 | 0.71 | IDO1 (0.37) | MAPTMEN1KMT2AGRIA1CACNG8 | |
| SCHEMBL16016121 | 0.69 | PBRM1 (0.57) | MAPTMEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL10029693 | 0.68 | HSD17B1 (0.54) | MAPTSMN1; SMN2HSD17B10NPC1MITF | |
| SCHEMBL30846855 | 0.68 | PBRM1 (0.47) | MAPTNPC1MITFLMNAPOLB | |
| SCHEMBL8171792 | 0.67 | CYP3A4 (0.52) | MAPTMEN1KMT2ALMNACYP1A2 | |
| SCHEMBL12577690 | 0.67 | BRD4 (0.59) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL2020761 | 0.67 | KMO (0.60) | RXRARXRBSMN1; SMN2NPC1LMNA | |
| SCHEMBL4262253 | 0.67 | PARP1 (0.60) | MAPTHSD17B10POLBFFAR1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2964635-B1 | ANTIVIRAL COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2018-05-02 | — | — | EP | disclosed |