Sugi Predict

Sugi Predict / Compounds / SCHEMBL20108891

SCHEMBL20108891

SCHEMBL20108891

O=P(c1ccccc1)(c1ccccc1)c1ccc(-c2ncc(-c3ccc4ccc5cccnc5c4n3)cn2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NFKB1 P19838 3/20 0.39
▸ SMN1; SMN2 Q16637 3/20 0.39
▸ MMP2 P08253 2/20 0.39
▸ CCR1 P32246 2/20 0.39
▸ CCR5 P51681 2/20 0.39
▸ CCR8 P51685 2/20 0.39
▸ LMNA P02545 2/20 0.39
▸ KDM4E B2RXH2 1/20 0.39
▸ GMNN O75496 1/20 0.39
▸ TP53 P04637 1/20 0.39
▸ HSP90AA1 P07900 1/20 0.39
▸ CYP3A4 P08684 1/20 0.39
▸ CYP2D6 P10635 1/20 0.39
▸ MAPT P10636 1/20 0.39
▸ MMP9 P14780 1/20 0.39
▸ ALOX15 P16050 1/20 0.39
▸ TSHR P16473 1/20 0.39
▸ MMP8 P22894 1/20 0.39
▸ THPO P40225 1/20 0.39
▸ MTOR P42345 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17403770 0.90 MMP2 (0.46) NFKB1SMN1; SMN2MMP2CCR1CCR5
SCHEMBL20108872 0.85 CCR1 (0.41) NFKB1SMN1; SMN2MMP2CCR1CCR5
SCHEMBL20967334 0.85 TOP1 (0.46) NFKB1SMN1; SMN2MMP2CCR1CCR5
SCHEMBL19763016 0.84 NFKB1 (0.51) NFKB1SMN1; SMN2MMP2CCR1CCR5
SCHEMBL17451965 0.84 TOP1 (0.42) NFKB1SMN1; SMN2MMP2CCR1CCR5
SCHEMBL20108852 0.83 TOP1 (0.41) NFKB1SMN1; SMN2MMP2CCR1CCR5
SCHEMBL26542763 0.83 SMN1; SMN2 (0.50) NFKB1SMN1; SMN2MMP2CCR1CCR5
SCHEMBL17174206 0.82 CCR1 (0.43) NFKB1SMN1; SMN2MMP2CCR1CCR5
SCHEMBL20108874 0.82 TOP1 (0.38) NFKB1SMN1; SMN2MMP2CCR1CCR5
SCHEMBL20108867 0.81 LMNA (0.40) NFKB1SMN1; SMN2MMP2CCR1CCR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11155543-B2 Organic compound, and organic light emitting diode and organic light emitting display device including the same LG DISPLAY CO., LTD. (KR) 2021-10-26 — — US disclosed
US-20180118742-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2018-05-03 — — US disclosed
US-20180118742-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2018-05-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180118742-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE INCLUDING THE SAME OCIAD2, OCIAD1, PPOX NFKB1 4112/4885SMN1; SMN2 2603/4885MMP2 2294/4885
US-11155543-B2 Organic compound, and organic light emitting diode and organic light emitting display device including the same OCIAD2, OCIAD1, PPOX NFKB1 4112/4885SMN1; SMN2 2603/4885MMP2 2294/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.