Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.39 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL565487 | 0.90 | ALDH1A1 (0.50) | ALDH1A1KMT2AMAPTL3MBTL1MEN1 | |
| SCHEMBL13221149 | 0.81 | ALDH1A1 (0.53) | ALDH1A1KMT2AMAPTL3MBTL1MEN1 | |
| SCHEMBL5144244 | 0.80 | SRC (0.47) | ALDH1A1KMT2AMAPTL3MBTL1MEN1 | |
| SCHEMBL14195844 | 0.79 | S1PR2 (0.50) | ALDH1A1KMT2AMAPTL3MBTL1MEN1 | |
| SCHEMBL5351709 | 0.79 | SRC (0.53) | ALDH1A1KMT2AMAPTL3MBTL1MEN1 | |
| SCHEMBL8035224 | 0.77 | THRA (0.51) | ALDH1A1KMT2AMAPTMEN1SRC | |
| SCHEMBL8612271 | 0.75 | SRC (0.50) | ALDH1A1KMT2AMAPTL3MBTL1MEN1 | |
| SCHEMBL30902486 | 0.75 | ALDH1A1 (0.59) | ALDH1A1KMT2AMAPTL3MBTL1MEN1 | |
| SCHEMBL4005149 | 0.75 | ALDH1A1 (0.46) | ALDH1A1KMT2AMAPTL3MBTL1MEN1 | |
| SCHEMBL7679676 | 0.75 | SRC (0.46) | ALDH1A1KMT2AMAPTL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180118679-A1 | N-Methyl Pyrazoles | Prosetta Antiviral ,Inc. | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180118679-A1 | N-Methyl Pyrazoles | ZC3HAV1, MAVS, NNMT | ALDH1A1 3967/4885KMT2A 768/4885MAPT 1058/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.