Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | RXRA | P19793 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | ASPH | Q12797 | 1/20 | 0.50 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.49 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30893766 | 0.89 | NPC1 (0.62) | RAB9ANPC1SMN1; SMN2POLBRXRA | |
| SCHEMBL27200112 | 0.89 | NPC1 (0.62) | RAB9ANPC1SMN1; SMN2POLBRXRA | |
| SCHEMBL8882537 | 0.88 | MAPT (0.52) | RAB9ANPC1SMN1; SMN2RXRAKDM4E | |
| SCHEMBL784068 | 0.88 | RAB9A (0.60) | RAB9ANPC1SMN1; SMN2POLBKDM4E | |
| SCHEMBL8883654 | 0.86 | RXRA (0.50) | RAB9ANPC1RXRAKDM4EATM | |
| SCHEMBL8785130 | 0.85 | MRGPRX4 (0.55) | RAB9ASMN1; SMN2ABCB1TP53PKM | |
| SCHEMBL30848623 | 0.85 | LTA4H (0.58) | RXRAKDM4EALDH1A1PPIARXRB | |
| SCHEMBL2426791 | 0.85 | LTA4H (0.58) | RXRAKDM4EALDH1A1PPIARXRB | |
| SCHEMBL8883987 | 0.84 | KMT2A (0.56) | RAB9ANPC1RXRAPPIARXRB | |
| Hydrochloric Acid SCHEMBL10705444 | 0.84 | LTA4H (0.57) | RXRAKDM4EALDH1A1PPIARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120071322-A1 | Substituted Pyridopyrazines with a Herbicidal Action | BASF SE (DE) | 2012-03-22 | — | — | US | disclosed |
| EP-2379503-A1 | HETEROCYCLIC DIKETONE DERIVATIVES WITH HERBICIDAL ACTION | BASF SE (DE) | 2011-10-26 | — | — | EP | disclosed |
| US-20110251063-A1 | HETEROCYCLIC DIKETONE DERIVATIVES WITH HERBICIDAL ACTION | BASF SE (DE) | 2011-10-13 | — | — | US | disclosed |
| WO-2011064188-A1 | INSECTICIDAL METHODS USING NITROGEN-CONTAINING HETEROAROMATIC COMPOUNDS | BASF SE (DE) | 2011-06-03 | — | — | WO | disclosed |
| WO-2010139658-A1 | SUBSTITUTED PYRIDOPYRAZINES WITH A HERBICIDAL ACTION | BASF SE (DE) | 2010-12-09 | — | — | WO | disclosed |
| WO-2010069802-A1 | HETEROCYCLIC DIKETONE DERIVATIVES WITH HERBICIDAL ACTION | BASF SE (DE) | 2010-06-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071322-A1 | Substituted Pyridopyrazines with a Herbicidal Action | PLPBP, PNPO, PFAS | RAB9A 3862/4885NPC1 4846/4885SMN1; SMN2 4015/4885 |
| US-20110251063-A1 | HETEROCYCLIC DIKETONE DERIVATIVES WITH HERBICIDAL ACTION | DDT, KHK, HK1 | RAB9A 3291/4885NPC1 4587/4885SMN1; SMN2 4548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.