Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 6/20 | 0.58 |
| ▸ | CA2 | P00918 | 6/20 | 0.58 |
| ▸ | CA1 | P00915 | 5/20 | 0.58 |
| ▸ | CA12 | O43570 | 4/20 | 0.58 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6917519 | 0.80 | MGLL (0.50) | NPSR1LMNAALDH1A1 | |
| SCHEMBL18173518 | 0.78 | CA12 (0.56) | CA9CA2CA1CA12KMT2A | |
| SCHEMBL2412820 | 0.77 | CA1 (0.69) | CA9CA2CA1CA12SCN2A | |
| SCHEMBL9438146 | 0.77 | CA1 (0.73) | CA9CA2CA1CA12SCN2A | |
| SCHEMBL10823807 | 0.76 | CA1 (0.43) | CA9CA2CA1LMNAALDH1A1 | |
| SCHEMBL2850335 | 0.76 | CA2 (0.44) | CA9CA2CA1CA12SCN2A | |
| SCHEMBL18180096 | 0.76 | CA2 (0.37) | CA9CA2CA1CA12KMT2A | |
| SCHEMBL11031364 | 0.76 | CA1 (0.35) | CA9CA2CA1CA12 | |
| SCHEMBL16702445 | 0.75 | CA12 (0.33) | CA9CA2CA1CA12SCN2A | |
| SCHEMBL81874 | 0.74 | HTR6 (0.44) | CA9CA2CA1CA12NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180118857-A1 | PROCESS FOR FUNCTIONALISING POLYMERS | WILMINGTON TRUST (LONDON) LIMITED, AS COLLATERAL AGENT (GB) | 2018-05-03 | — | — | US | disclosed |
| US-20180118857-A1 | PROCESS FOR FUNCTIONALISING POLYMERS | WILMINGTON TRUST (LONDON) LIMITED, AS COLLATERAL AGENT (GB) | 2018-05-03 | — | — | US | disclosed |