Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20113637 | 0.84 | GRM1 (0.32) | GRM1 | |
| SCHEMBL20113671 | 0.81 | GLP1R (0.33) | ALDH1A1GRM1 | |
| SCHEMBL20113649 | 0.80 | MEN1 (0.37) | ALDH1A1GRM1LMNA | |
| SCHEMBL9846251 | 0.79 | GRM1 (0.37) | ALDH1A1GRM1LMNA | |
| SCHEMBL20113662 | 0.75 | — | — | |
| SCHEMBL686307 | 0.75 | ALDH1A1 (0.39) | ALDH1A1LMNA | |
| SCHEMBL28423423 | 0.75 | SRC (0.41) | ALDH1A1LMNACYP2C19 | |
| SCHEMBL20113952 | 0.74 | CYP1A2 (0.39) | ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL20113696 | 0.71 | MEN1 (0.36) | ALDH1A1LMNA | |
| SCHEMBL20113756 | 0.68 | CCR1 (0.41) | ALDH1A1GRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3060563-B1 | RING-FUSED BICYCLIC PYRIDYL DERIVATIVES AS FGFR4 INHIBITORS | NOVARTIS AG (CH) | 2018-05-02 | — | — | EP | disclosed |