Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 12/20 | 0.36 |
| ▸ | ITGAV | P06756 | 12/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9398036 | 0.88 | ITGB3 (0.40) | ITGB3ITGAVITGA2BKMT2AATM | |
| SCHEMBL6687766 | 0.77 | ALDH1A1 (0.42) | KMT2AATMALDH1A1PKML3MBTL1 | |
| SCHEMBL1477670 | 0.76 | ALDH1A1 (0.49) | NAPRTALDH1A1PKML3MBTL1KDM4E | |
| SCHEMBL9607 | 0.75 | KMT2A (0.43) | KMT2AATMALDH1A1PKM | |
| SCHEMBL9398017 | 0.72 | ALDH1A1 (0.48) | KMT2AALDH1A1PKML3MBTL1KDM4E | |
| SCHEMBL10980060 | 0.70 | KMT2A (0.38) | KMT2AATMALDH1A1PKM | |
| SCHEMBL616909 | 0.68 | ALDH1A1 (0.43) | KMT2AATMALDH1A1PKML3MBTL1 | |
| SCHEMBL28946087 | 0.67 | LMNA (0.44) | KMT2ANAPRTALDH1A1L3MBTL1KDM4E | |
| SCHEMBL1477669 | 0.67 | SLC22A12 (0.36) | KMT2AALDH1A1L3MBTL1KDM4E | |
| SCHEMBL8082242 | 0.66 | EHMT2 (0.38) | KMT2AALDH1A1PKML3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011072627-A2 | DENDRITIC HIGH-MOLECULAR-WEIGHT POLYMER DRUG CARRIERS AND THEIR CONJUGATES WITH DRUGS ESPECIALLY FOR TREATMENT OF SOLID TUMOURS | USTAV MAKROMOLEKULARNI CHEMIE AV CR, V.V.I. (CZ) | 2011-06-23 | — | — | WO | disclosed |