Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 3/20 | 0.36 |
| ▸ | FNTB | P49356 | 3/20 | 0.36 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.36 |
| ▸ | RORC | P51449 | 7/20 | 0.35 |
| ▸ | USP14 | P54578 | 2/20 | 0.32 |
| ▸ | TDP2 | O95551 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20116769 | 0.94 | RORC (0.36) | RORCUSP14TDP2PPARGPTGER4 | |
| SCHEMBL19380368 | 0.87 | USP14 (0.36) | RORCUSP14TDP2PTGER4KDM1A | |
| SCHEMBL26831723 | 0.80 | RORC (0.40) | RORCPTGER4 | |
| SCHEMBL17424694 | 0.80 | RORC (0.40) | RORCPTGER4 | |
| SCHEMBL17424670 | 0.80 | RORC (0.40) | RORCPTGER4 | |
| SCHEMBL17424684 | 0.80 | RORC (0.40) | RORCPTGER4 | |
| SCHEMBL20116770 | 0.80 | USP14 (0.35) | RORCUSP14PPARGAR | |
| SCHEMBL23624455 | 0.79 | KIF11 (0.45) | RORCUSP14PPARGPTGER4 | |
| SCHEMBL24617044 | 0.79 | KIF11 (0.45) | RORCUSP14PPARGPTGER4 | |
| SCHEMBL17115476 | 0.79 | CSNK1D (0.39) | RORCUSP14PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3119770-B1 | NEW DIBENZOFURANS AND DIBENZOTHIOPHENES | IDEMITSU KOSAN CO (JP) | 2018-05-02 | — | — | EP | disclosed |