Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP14 | P54578 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 6/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19380368 | 0.92 | USP14 (0.36) | USP14RORCARSLC22A12 | |
| SCHEMBL20116769 | 0.85 | RORC (0.36) | USP14RORCARPPARGSLC22A12 | |
| SCHEMBL20116772 | 0.80 | RORC (0.39) | RORC | |
| SCHEMBL20115889 | 0.80 | FNTA (0.36) | USP14RORCARPPARG | |
| SCHEMBL18707066 | 0.79 | G6PD (0.38) | USP14RORCKDM4EALDH1A1AR | |
| SCHEMBL17115472 | 0.79 | USP14 (0.36) | USP14LMNARORCKDM4EALDH1A1 | |
| SCHEMBL20116771 | 0.78 | RORC (0.32) | RORCALDH1A1 | |
| SCHEMBL20115895 | 0.78 | KDM1A (0.44) | USP14RORCKDM4EALDH1A1 | |
| SCHEMBL17115336 | 0.77 | USP14 (0.35) | USP14LMNARORCKDM4EALDH1A1 | |
| SCHEMBL18713377 | 0.77 | USP14 (0.35) | USP14LMNARORCKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3119770-B1 | NEW DIBENZOFURANS AND DIBENZOTHIOPHENES | IDEMITSU KOSAN CO (JP) | 2018-05-02 | — | — | EP | disclosed |