Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.40 |
| ▸ | TBK1 | Q9UHD2 | 3/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.38 |
| ▸ | CPT1A | P50416 | 2/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | USP7 | Q93009 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CPT2 | P23786 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20117281 | 0.93 | TBK1 (0.36) | USP30TBK1FLT3IKBKECPT1A | |
| SCHEMBL20116814 | 0.87 | USP30 (0.53) | USP30TBK1CPT1AKIT | |
| SCHEMBL20116816 | 0.83 | TBK1 (0.39) | TBK1FLT3IKBKECPT1AKIT | |
| SCHEMBL20117204 | 0.82 | TBK1 (0.38) | USP30TBK1CPT1AKITUSP7 | |
| SCHEMBL20676436 | 0.80 | USP7 (0.41) | USP30CPT1AKITUSP7SMN1; SMN2 | |
| SCHEMBL20116785 | 0.79 | KIT (0.42) | USP30CPT1AKITUSP7SMN1; SMN2 | |
| SCHEMBL20116775 | 0.78 | SMN1; SMN2 (0.41) | USP30TBK1CPT1AKITHSD11B1 | |
| SCHEMBL20116368 | 0.77 | USP30 (0.42) | USP30HSD11B1USP7SMN1; SMN2ALDH1A1 | |
| SCHEMBL20116844 | 0.76 | MAPT (0.35) | S1PR1 | |
| SCHEMBL20117192 | 0.73 | TLR9 (0.51) | SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081167-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS (US) | 2018-05-03 | — | — | WO | disclosed |