Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 5/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | APLNR | P35414 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20116772 | 0.86 | RORC (0.39) | RORC | |
| SCHEMBL19380368 | 0.83 | USP14 (0.36) | RORC | |
| SCHEMBL17115464 | 0.82 | RORC (0.32) | RORC | |
| SCHEMBL18707022 | 0.82 | HPGD (0.33) | RORCKMT2A | |
| SCHEMBL17115482 | 0.81 | HPGD (0.33) | RORCKMT2A | |
| SCHEMBL17115477 | 0.81 | HPGD (0.33) | RORCKMT2A | |
| SCHEMBL17115381 | 0.80 | PTGER4 (0.33) | RORC | |
| SCHEMBL20116770 | 0.78 | USP14 (0.35) | RORCALDH1A1 | |
| SCHEMBL20116769 | 0.77 | RORC (0.36) | RORC | |
| SCHEMBL17115369 | 0.77 | PTGER4 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3119770-B1 | NEW DIBENZOFURANS AND DIBENZOTHIOPHENES | IDEMITSU KOSAN CO (JP) | 2018-05-02 | — | — | EP | disclosed |