Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CCR9 | P51686 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22357747 | 0.85 | CYP26A1 (0.38) | KMOALDH1A1POLBHSD17B10TSHR | |
| SCHEMBL25696305 | 0.79 | KMO (0.45) | KMOALDH1A1TSHRCYP1A2CYP2C9 | |
| SCHEMBL15339562 | 0.76 | ALDH1A1 (0.38) | ALDH1A1POLBHSD17B10CYP4F2CYP4A11 | |
| SCHEMBL20116286 | 0.73 | KMO (0.42) | KMOALDH1A1TSHRCYP1A2CYP2C9 | |
| SCHEMBL16985359 | 0.72 | CYP4F2 (0.39) | ALDH1A1HSD17B10TSHRCYP4F2CYP4A11 | |
| SCHEMBL20116570 | 0.70 | CYP4F2 (0.44) | ALDH1A1ADORA3POLBHSD17B10TSHR | |
| SCHEMBL21611270 | 0.70 | KMO (0.54) | KMOALDH1A1ADORA3POLBHSD17B10 | |
| SCHEMBL21850227 | 0.70 | ALDH1A1 (0.39) | ALDH1A1HSD17B10TSHRCYP4F2CYP4A11 | |
| SCHEMBL9877609 | 0.69 | SMN1; SMN2 (0.51) | ALDH1A1HSD17B10TSHRCYP1A2CYP2C9 | |
| SCHEMBL29901474 | 0.67 | KMO (0.57) | KMOCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019209948-A9 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-01-02 | — | — | WO | disclosed |
| WO-2019018795-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS (US) | 2019-01-24 | — | — | WO | disclosed |
| WO-2018081167-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS (US) | 2018-05-03 | — | — | WO | disclosed |