Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.65 |
| ▸ | APP | P05067 | 3/20 | 0.60 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.59 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | SNCA | P37840 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | PTGES | O14684 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19695927 | 0.95 | FDPS (0.73) | FDPSAPPPDE4BNFE2L2ALDH1A1 | |
| SCHEMBL9901361 | 0.85 | FDPS (0.60) | FDPSAPPPDE4BNFE2L2ALDH1A1 | |
| SCHEMBL9901365 | 0.85 | FDPS (0.60) | FDPSAPPPDE4BNFE2L2ALDH1A1 | |
| SCHEMBL9901363 | 0.85 | FDPS (0.60) | FDPSAPPPDE4BNFE2L2ALDH1A1 | |
| SCHEMBL30289943 | 0.84 | KDM4E (0.69) | FDPSNFE2L2ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL20455920 | 0.84 | KDM4E (0.69) | FDPSNFE2L2ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL21715528 | 0.84 | KDM4E (0.69) | FDPSNFE2L2ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL12336758 | 0.84 | NFE2L2 (0.72) | FDPSAPPNFE2L2ALDH1A1SMN1; SMN2 | |
| SCHEMBL2743855 | 0.84 | HTT (0.66) | FDPSAPPNFE2L2ALDH1A1SMN1; SMN2 | |
| SCHEMBL2743857 | 0.84 | HTT (0.66) | FDPSAPPNFE2L2ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10695353-B2 | Methods of treating eye diseases associated with inflammation and vascular proliferation | OCCURX PTY LTD (AU) | 2020-06-30 | — | — | US | disclosed |
| US-20180117051-A1 | METHODS OF TREATING EYE DISEASES ASSOCIATED WITH INFLAMMATION AND VASCULAR PROLIFERATION | OCCURX PTY LTD (AU) | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10695353-B2 | Methods of treating eye diseases associated with inflammation and vascular proliferation | VCAM1, PTGIS, NFKBIA | FDPS 2234/4885APP 3849/4885PDE4B 2154/4885 |
| US-20180117051-A1 | METHODS OF TREATING EYE DISEASES ASSOCIATED WITH INFLAMMATION AND VASCULAR PROLIFERATION | VCAM1, PTGIS, NFKBIA | FDPS 2234/4885APP 3849/4885PDE4B 2154/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.