Formamide

Formamide

SCHEMBL2011773

CCc1ccsc1CC.NC=O

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 1/20 0.34
ALOX5 P09917 1/20 0.33
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17318736 0.90 KEAP1 (0.33) KEAP1ALOX5
SCHEMBL1709256 0.89
Ammonia Solution, Strong SCHEMBL29003993 0.87 KEAP1 (0.34) KEAP1ALOX5ALDH1A1MAPTLMNA
Carbamic Acid SCHEMBL9006901 0.82 ALOX5 (0.42) KEAP1ALOX5ALDH1A1MAPT
Carbamic Acid SCHEMBL10511096 0.80 ALOX5 (0.41) ALOX5ALDH1A1MAPT
SCHEMBL20825108 0.78
SCHEMBL20561910 0.74
SCHEMBL14015619 0.74 LTB4R (0.36) KEAP1ALOX5
SCHEMBL9354723 0.74
SCHEMBL9355009 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0322164-B1 ETHANOLAMINE DERIVATIVES GLAXO GROUP LIMITED (GB) 1993-09-22 EP claimed
CN-118076711-A Polymerizable compound, polymerizable LC material and polymer film 默克专利股份有限公司 2024-05-24 CN disclosed
CN-110724136-B Amide compound and preparation method and application thereof 沈阳中化农药化工研发有限公司 2023-02-17 CN disclosed
CN-110179777-B Pharmaceutical compositions comprising nitroxyl donors 卡尔迪奥克斯尔制药公司 2022-07-15 CN disclosed
CN-110724136-A Amide compound and preparation method and application thereof 沈阳中化农药化工研发有限公司 2020-01-24 CN disclosed
CN-105968124-A 2,6-bis(triphenylamine)-4,8-bis(alkoxy)benzo[1,2-b:4,5-b']bithiophene and preparation for same 华东师范大学 2016-09-28 CN disclosed
CN-105968125-A Hole transporting material for perovskite solar cell and application thereof 华东师范大学 2016-09-28 CN disclosed
EP-2507287-A1 NOVEL PHOTOACTIVE POLYMERS Université Laval (CA) 2012-10-10 EP disclosed
WO-2011063534-A1 NOVEL PHOTOACTIVE POLYMERS UNIVERSITé LAVAL (CA) 2011-06-03 WO disclosed
EP-0649414-B1 OPIOID DIARYLMETHYLPIPERAZINES AND PIPERIDINES ARDENT PHARMACEUTICALS INC (US) 2003-04-16 EP disclosed
EP-0649414-A1 OPIOID DIARYLMETHYLPIPERAZINES AND PIPERIDINES THE WELLCOME FOUNDATION LIMITED (GB) 1995-04-26 EP disclosed
EP-0322164-B1 ETHANOLAMINE DERIVATIVES GLAXO GROUP LIMITED (GB) 1993-09-22 EP disclosed
WO-1993015062-A1 OPIOID DIARYLMETHYLPIPERAZINES AND PIPERIDINES THE WELLCOME FOUNDATION LIMITED (GB) 1993-08-05 WO disclosed
EP-0342433-A2 Substituted dibenzothiaphenes AMERICAN CYANAMID COMPANY (US) 1989-11-23 EP disclosed