Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL29003993

CCc1ccsc1CC.N

nearest known ligand 0.34

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Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 1/20 0.34
ALOX5 P09917 1/20 0.32
GABRA1 P14867 2/20 0.32
GABRB2 P47870 2/20 0.32
RIPK1 Q13546 1/20 0.32
LTB4R Q15722 4/20 0.31
ALDH1A1 P00352 2/20 0.31
MAPT P10636 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1709256 0.97
Formamide SCHEMBL2011773 0.87 KEAP1 (0.34) KEAP1ALOX5ALDH1A1MAPTLMNA
SCHEMBL27487261 0.86
SCHEMBL17318736 0.85 KEAP1 (0.33) KEAP1ALOX5
Carbamic Acid SCHEMBL9006901 0.85 ALOX5 (0.42) KEAP1ALOX5RIPK1LTB4RALDH1A1
Carbamic Acid SCHEMBL10511096 0.83 ALOX5 (0.41) ALOX5RIPK1LTB4RALDH1A1MAPT
SCHEMBL20825108 0.81
SCHEMBL20561910 0.81
SCHEMBL9354723 0.81
SCHEMBL14015619 0.81 LTB4R (0.36) KEAP1ALOX5GABRA1GABRB2RIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116143722-B Synthesis process of sulfenamide compound 南京师范大学 2024-05-31 CN disclosed
CN-116143722-A Synthesis process of sulfenamide compound 南京师范大学 2023-05-23 CN disclosed