Carbamic Acid

Carbamic Acid

SCHEMBL9006901

CCc1ccsc1CC.NC(=O)O

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.42
LTB4R Q15722 7/20 0.36
MAPT P10636 2/20 0.35
MAPK1 P28482 2/20 0.35
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
ALDH1A1 P00352 1/20 0.35
BCAT2 O15382 1/20 0.34
RIPK1 Q13546 1/20 0.34
KEAP1 Q14145 1/20 0.33
KDM4E B2RXH2 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
GAA P10253 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
PTK2 Q05397 1/20 0.33
ABCC1 P33527 1/20 0.33
TP53 P04637 1/20 0.33
ALOX15 P16050 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Carbamic Acid SCHEMBL10511096 0.98 ALOX5 (0.41) ALOX5LTB4RMAPTMAPK1KMT2A
SCHEMBL1709256 0.87
Ammonia Solution, Strong SCHEMBL29003993 0.85 KEAP1 (0.34) ALOX5LTB4RMAPTALDH1A1RIPK1
SCHEMBL367774 0.82 AKR1B1 (0.39) ALOX5LTB4RMAPK1KMT2AALDH1A1
Formamide SCHEMBL2011773 0.82 KEAP1 (0.34) ALOX5MAPTALDH1A1KEAP1
SCHEMBL17318736 0.80 KEAP1 (0.33) ALOX5KEAP1
SCHEMBL4600787 0.80 PTGDR2 (0.41) ALOX5LTB4RMAPK1KMT2AMEN1
Carbamic Acid SCHEMBL27276269 0.79 LTB4R (0.43) ALOX5LTB4RMAPTMAPK1KMT2A
SCHEMBL4599796 0.77 LTB4R (0.51) LTB4RMAPTKMT2AMEN1ALDH1A1
SCHEMBL20825108 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-54055725-A None JP disclosed
JP-59073505-A None JP disclosed
US-5500408-A NONPHYTOTOXIC TOSOH CORPORATION (JP) 1996-03-19 US disclosed
CN-86103671-A HERBICIDAL COMPOSITIONS 1986-12-17 CN disclosed
JP-S5973505-A HERBICIDE FOR PADDY FIELD YASHIMA CHEM IND CO LTD 1984-04-25 JP disclosed
JP-S5455725-A HERICIDE COMPOSITION FOR PADDY RICE FIELD ASAHI CHEM IND CO LTD 1979-05-04 JP disclosed