Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | IRAK4 | Q9NWZ3 | 17/20 | 0.45 |
| ▸ | IRAK1 | P51617 | 3/20 | 0.43 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20118183 | 0.92 | KDM4E (0.45) | KDM4EHSD17B10IRAK4IRAK1TNKS | |
| SCHEMBL20118187 | 0.83 | PDE4B (0.41) | TNKS | |
| SCHEMBL20118220 | 0.83 | ALDH1A1 (0.50) | KDM4EHSD17B10 | |
| SCHEMBL20118213 | 0.82 | LMNA (0.42) | TNKS | |
| SCHEMBL18209065 | 0.81 | IRAK4 (0.49) | KDM4EHSD17B10IRAK4IRAK1TNKS | |
| SCHEMBL18208502 | 0.81 | IRAK4 (0.49) | KDM4EHSD17B10IRAK4IRAK1TNKS | |
| SCHEMBL18208548 | 0.81 | IRAK4 (0.49) | KDM4EHSD17B10IRAK4IRAK1TNKS | |
| SCHEMBL20185045 | 0.81 | KDM4E (0.46) | KDM4EHSD17B10IRAK4IRAK1TNKS | |
| SCHEMBL20185038 | 0.81 | KDM4E (0.46) | KDM4EHSD17B10IRAK4IRAK1TNKS | |
| SCHEMBL20185046 | 0.81 | KDM4E (0.46) | KDM4EHSD17B10IRAK4IRAK1TNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018078009-A1 | AMIDO-SUBSTITUTED CYCLOHEXANE DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-05-03 | — | — | WO | disclosed |