SCHEMBL20118986

SCHEMBL20118986

[N-]=[N+]=NS(=O)(=O)c1ccc(N2C(=O)CCC2O)cc1

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 1/20 0.32
AKR1C3 P42330 2/20 0.32
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31
PTGER3 P43115 1/20 0.31
PTGER2 P43116 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18173518 0.76 CA12 (0.56) CA12CA1CA2CA9
SCHEMBL10823807 0.71 CA1 (0.43) CA1CA2CA9
SCHEMBL11031364 0.70 CA1 (0.35) CA12CA1CA2CA9
SCHEMBL20111164 0.70 MAPT (0.44) CA12CA1CA2CA9
SCHEMBL22693760 0.68 MT-CO2 (0.37) CA12CA1CA2CA9
SCHEMBL6917519 0.68 MGLL (0.50)
SCHEMBL18180096 0.68 CA2 (0.37) CA12CA1CA2CA9
SCHEMBL9645847 0.66 LMNA (0.46) CA12CA1CA2CA9
SCHEMBL29188737 0.66 ALDH1A1 (0.36)
SCHEMBL5676376 0.66 CA2 (0.41) CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180118857-A1 PROCESS FOR FUNCTIONALISING POLYMERS WILMINGTON TRUST (LONDON) LIMITED, AS COLLATERAL AGENT (GB) 2018-05-03 US disclosed