Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR17 | Q13304 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KLK6 | Q92876 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23226282 | 0.82 | APEX1 (0.39) | HSD17B10KLK6SMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL20119872 | 0.82 | EGFR (0.46) | HSD17B10KLK6SMN1; SMN2MEN1KMT2A | |
| SCHEMBL18029302 | 0.81 | TPH1 (0.42) | KLK6SMN1; SMN2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL21392202 | 0.78 | ALDH1A1 (0.37) | KLK6SMN1; SMN2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL20120180 | 0.77 | HSD17B10 (0.42) | HSD17B10SMN1; SMN2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL19872653 | 0.77 | GPR17 (0.44) | GPR17HSD17B10SMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL18509957 | 0.77 | FBP1 (0.48) | ALDH1A1CYP2C19L3MBTL1MAPTKDM4E | |
| SCHEMBL21392019 | 0.76 | GPR17 (0.51) | GPR17ALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL21392032 | 0.76 | KLK6 (0.47) | GPR17KLK6ALDH1A1APEX1MEN1 | |
| SCHEMBL21392230 | 0.75 | KIF11 (0.50) | HSD17B10KLK6ALDH1A1ALOX15APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183358-A2 | WHOLE CELL PROCESSES TO PRODUCE NITROAROMATICS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2019-09-26 | — | — | WO | disclosed |
| WO-2018081456-A1 | HIGHLY ACTIVE SELF-SUFFICIENT NITRATION BIOCATALYSTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2018-05-03 | — | — | WO | disclosed |