Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.48 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8325496 | 0.85 | CNR1 (0.52) | MAPTALDH1A1LMNAPDE3BPDE3A | |
| SCHEMBL6706308 | 0.84 | TSHR (0.63) | LMNAL3MBTL1TSHR | |
| SCHEMBL12036216 | 0.84 | CNR1 (0.48) | MAPTALDH1A1LMNAPDE3BPDE3A | |
| SCHEMBL4529316 | 0.83 | ALDH1A1 (0.54) | MAPTALDH1A1LMNAPDE3BPDE3A | |
| SCHEMBL14123954 | 0.83 | CNR1 (0.47) | MAPTALDH1A1LMNAPDE3BPDE3A | |
| SCHEMBL6321351 | 0.78 | HPGD (0.54) | ALDH1A1PDK2HPGDMEN1KMT2A | |
| SCHEMBL14586326 | 0.78 | LMNA (0.49) | MAPTALDH1A1LMNAPDE3BPDE3A | |
| SCHEMBL9923769 | 0.77 | HPGD (0.64) | MAPTALDH1A1LMNASMN1; SMN2HPGD | |
| SCHEMBL13784819 | 0.77 | THRA (0.47) | MAPTLMNASMN1; SMN2L3MBTL1TSHR | |
| SCHEMBL16480609 | 0.76 | L3MBTL1 (0.44) | MAPTALDH1A1LMNASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE46830-E1 | Method for solid phase peptide synthesis | POLYPEPTIDE LABORATORIES HOLDING (PPL) AB (SE) | 2018-05-08 | — | — | US | disclosed |