Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | LOX | P28300 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20031366 | 0.86 | NOS3 (0.47) | LOXL2NOS3NOS2LOXADRB2 | |
| SCHEMBL17808255 | 0.82 | NOS3 (0.37) | LOXL2NOS3NOS2LOXADRB2 | |
| SCHEMBL18532052 | 0.82 | LMNA (0.35) | TDP1NPC1RAB9ALMNAMAPK1 | |
| SCHEMBL18699091 | 0.81 | MAPK1 (0.36) | TDP1NPC1RAB9ALMNAMAPK1 | |
| SCHEMBL18745826 | 0.81 | LOXL2 (0.49) | LOXL2NOS3NOS2LOXADRB2 | |
| SCHEMBL18532099 | 0.77 | ALDH1A1 (0.40) | TDP1NPC1RAB9ALMNAMAPK1 | |
| SCHEMBL22624035 | 0.75 | ALDH1A1 (0.40) | TDP1NPC1RAB9ALMNAMAPK1 | |
| SCHEMBL18415080 | 0.75 | LOXL2 (0.34) | LOXL2LOXNPC1RAB9ALMNA | |
| SCHEMBL22903529 | 0.74 | SMN1; SMN2 (0.38) | ADRB2TDP1NPC1RAB9ALMNA | |
| SCHEMBL13998515 | 0.73 | UHRF1 (0.45) | NOS3NOS2NPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9963445-B2 | Chemical compounds | SYNGENTA LIMITED (GB) | 2018-05-08 | — | — | US | disclosed |