Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20123640 | 0.86 | NOTUM (0.36) | NOTUM | |
| SCHEMBL20123626 | 0.86 | NOTUM (0.36) | NOTUMDRD2DRD3 | |
| SCHEMBL20015251 | 0.85 | NOTUM (0.36) | NOTUMDRD2DRD3 | |
| SCHEMBL20014966 | 0.83 | NOTUM (0.40) | NOTUMDRD2DRD3 | |
| SCHEMBL19939720 | 0.80 | ALDH1A1 (0.34) | NOTUMDRD2DRD3 | |
| SCHEMBL1912510 | 0.77 | — | — | |
| SCHEMBL20123649 | 0.76 | ACHE (0.35) | NOTUM | |
| SCHEMBL21183818 | 0.76 | NOTUM (0.33) | NOTUM | |
| SCHEMBL20014575 | 0.76 | ADRA2A (0.33) | NOTUM | |
| SCHEMBL20014568 | 0.76 | NOTUM (0.39) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2620436-B1 | SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG | SHIONOGI & CO (JP) | 2018-05-09 | — | — | EP | disclosed |