Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20123727 | 0.87 | ACHE (0.35) | ACHENOTUMLMNAMAPTHTT | |
| SCHEMBL20015251 | 0.86 | NOTUM (0.36) | NOTUM | |
| SCHEMBL20123632 | 0.86 | MEN1 (0.37) | LMNAMEN1KMT2ANPC1TP53 | |
| SCHEMBL21183818 | 0.81 | NOTUM (0.33) | NOTUM | |
| SCHEMBL20123600 | 0.81 | ADRA2A (0.33) | LMNANPSR1MEN1KMT2ANPC1 | |
| SCHEMBL20014575 | 0.81 | ADRA2A (0.33) | NOTUMNPSR1 | |
| SCHEMBL21183807 | 0.80 | CXCR5 (0.33) | MEN1KMT2A | |
| SCHEMBL20123641 | 0.78 | NOTUM (0.35) | NOTUM | |
| SCHEMBL20014966 | 0.78 | NOTUM (0.40) | ACHENOTUM | |
| SCHEMBL20123623 | 0.76 | NOTUM (0.42) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2620436-B1 | SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG | SHIONOGI & CO (JP) | 2018-05-09 | — | — | EP | disclosed |