Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PPID | Q08752 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16687713 | 0.84 | ALDH1A1 (0.51) | SMN1; SMN2LMNAALDH1A1MEN1TSHR | |
| SCHEMBL8342117 | 0.82 | FAP (0.45) | SMN1; SMN2LMNAEPHX2ALDH1A1MEN1 | |
| SCHEMBL11981577 | 0.81 | SMN1; SMN2 (0.41) | SMN1; SMN2LMNAEPHX2ALDH1A1MEN1 | |
| SCHEMBL11960546 | 0.80 | LMNA (0.47) | SMN1; SMN2LMNAEPHX2ALDH1A1MEN1 | |
| SCHEMBL8486131 | 0.80 | EPHX2 (0.44) | EPHX2ALDH1A1NPC1KDM4EKDM1A | |
| SCHEMBL15624816 | 0.77 | L3MBTL1 (0.46) | SMN1; SMN2ALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL13866398 | 0.76 | CPN1 (0.46) | EPHX2ALDH1A1NPC1KDM1AEPHX1 | |
| Hydrochloric Acid SCHEMBL15808554 | 0.75 | CPN1 (0.45) | EPHX2ALDH1A1NPC1KDM1AEPHX1 | |
| SCHEMBL8498758 | 0.75 | KDM1A (0.44) | SMN1; SMN2EPHX2ALDH1A1ITGB3ITGA2B | |
| SCHEMBL8485640 | 0.74 | EPHX2 (0.45) | EPHX2ALDH1A1NPC1KDM1AEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488532-B1 | ANTIMICROBIAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | MELINTA THERAPEUTICS INC (US) | 2018-05-09 | — | — | EP | disclosed |