Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.30 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20124703 | 0.92 | TAAR1 (0.33) | TAAR1PDE3BPDE3A | |
| SCHEMBL499758 | 0.84 | HTR2A (0.32) | CNR1CNR2GPR55SLC5A1LMNA | |
| SCHEMBL500101 | 0.76 | HTR2A (0.33) | SLC5A1LMNASLC5A2 | |
| SCHEMBL1010022 | 0.73 | ALDH1A1 (0.44) | SLC5A1TAAR1LMNASLC5A2PDE3B | |
| SCHEMBL15748708 | 0.72 | PKM (0.47) | SLC5A1KDM4ELMNASLC5A2 | |
| SCHEMBL37695 | 0.72 | KDM4E (0.44) | SLC5A1KDM4ESLC5A2PDE3BPDE3A | |
| SCHEMBL180996 | 0.71 | SLC5A1 (0.46) | CNR2SLC5A1LMNASLC5A2 | |
| SCHEMBL17175 | 0.70 | ESR1 (0.45) | KDM4E | |
| SCHEMBL15741057 | 0.70 | CCR5 (0.47) | SLC5A1 | |
| SCHEMBL2810557 | 0.70 | KDM4E (0.41) | TAAR1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3318562-A2 | BENZYLBENZENE DERIVATIVES AND METHODS OF USE | Theracos Sub, LLC (US) | 2018-05-09 | — | — | EP | disclosed |