SCHEMBL2012504

SCHEMBL2012504

Cc1cn([C@@]2(C)CC[C@@H](CO)O2)c(=O)[nH]c1=O

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.43
NPSR1 Q6W5P4 1/20 0.43
LMNA P02545 3/20 0.42
ALB P02768 2/20 0.42
BLM P54132 2/20 0.42
POLB P06746 1/20 0.42
ADRA1A P35348 1/20 0.42
TK1 P04183 6/20 0.41
TSHR P16473 2/20 0.37
PKM P14618 1/20 0.37
PMP22 Q01453 1/20 0.37
CYP2D6 P10635 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28765909 0.85 LMNA (0.42) ALDH1A1NPSR1LMNAALBBLM
SCHEMBL339966 0.84 ALDH1A1 (0.41) ALDH1A1NPSR1LMNAALBBLM
SCHEMBL1878105 0.84 ALDH1A1 (0.43) ALDH1A1NPSR1LMNAALBBLM
SCHEMBL3611848 0.84 LMNA (0.41) ALDH1A1NPSR1LMNAALBBLM
SCHEMBL30841853 0.84 ALDH1A1 (0.41) ALDH1A1NPSR1LMNAALBBLM
SCHEMBL27583424 0.84 ALDH1A1 (0.41) ALDH1A1NPSR1LMNAALBBLM
SCHEMBL2633815 0.82 LMNA (0.41) ALDH1A1NPSR1LMNAALBBLM
SCHEMBL4194798 0.81 ALDH1A1 (0.40) ALDH1A1NPSR1LMNAALBBLM
SCHEMBL135210 0.80 TK1 (0.44) ALDH1A1NPSR1LMNAALBBLM
SCHEMBL16187026 0.80 TK1 (0.44) ALDH1A1NPSR1LMNAALBBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7635467-B2 Mammalian multipotent stem cells and compositions, methods of preparation and methods of administration thereof THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2009-12-22 US claimed
US-7618621-B2 Mammalian multipotent neural stem cells and compositions, methods of preparation and methods of administration thereof THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2009-11-17 US claimed
US-9358234-B2 Mammalian multipotent stem cells and compositions, methods of preparation and methods of administration thereof THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2016-06-07 US disclosed
US-20140037589-A1 NOVEL MAMMALIAN MULTIPOTENT STEM CELLS AND COMPOSITIONS, METHODS OF PREPARATION AND METHODS OF ADMINISTRATION THEREOF THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS 2014-02-06 US disclosed
US-8192732-B2 Mammalian multipotent stem cells and compositions, methods of preparation and methods of administration thereof UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) 2012-06-05 US disclosed
WO-2011073218-A1 COMPOSITONS AND METHODS FOR INHIBITING EXPRESSION OF IL-18 GENES F. HOFFMANN-LA ROCHE AG (CH) 2011-06-23 WO disclosed
US-20100183567-A1 Novel Mammalian Multipotent Stem Cells and Compositions, Methods of Preparation and Methods of Administration Thereof THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS 2010-07-22 US disclosed
US-7635467-B2 Mammalian multipotent stem cells and compositions, methods of preparation and methods of administration thereof THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2009-12-22 US disclosed
US-7618621-B2 Mammalian multipotent neural stem cells and compositions, methods of preparation and methods of administration thereof THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2009-11-17 US disclosed
EP-1471970-A4 NOVEL MAMMALIAN MULTIPOTENT STEM CELLS AND COMPOSITIONS, METHODS OF PREPARATION AND METHODS OF ADMINISTRATION THEREOF UNIV ILLINOIS (US) 2006-08-02 EP disclosed
EP-1471970-A2 NOVEL MAMMALIAN MULTIPOTENT STEM CELLS AND COMPOSITIONS, METHODS OF PREPARATION AND METHODS OF ADMINISTRATION THEREOF BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2004-11-03 EP disclosed
US-20030219898-A1 Novel mammalian multipotent stem cells and compositions, methods of preparation and methods of administration thereof NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2003-11-27 US disclosed
US-20030148513-A1 Novel mammalian multipotent neural stem cells and compositions, methods of preparation and methods of administration thereof BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS, THE 2003-08-07 US disclosed
WO-2003060085-A2 MAMMALIAN NEURAL STEM CELLS, COMPOSITIONS AND USES THEREOF THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2003-07-24 WO disclosed
WO-2003059276-A2 NOVEL MAMMALIAN MULTIPOTENT STEM CELLS AND COMPOSITIONS, METHODS OF PREPARATION AND METHODS OF ADMINISTRATION THEREOF THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2003-07-24 WO disclosed