SCHEMBL4194798

SCHEMBL4194798

Cc1cn([C@@]2(C(=O)O)CC[C@@H](CO)O2)c(=O)[nH]c1=O

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.40
LMNA P02545 1/20 0.40
ALB P02768 1/20 0.40
POLB P06746 1/20 0.40
ADRA1A P35348 1/20 0.40
BLM P54132 1/20 0.40
TK1 P04183 4/20 0.39
NPSR1 Q6W5P4 1/20 0.39
TYMP P19971 1/20 0.38
RNASE1 P07998 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2012504 0.81 ALDH1A1 (0.43) ALDH1A1LMNAALBPOLBADRA1A
SCHEMBL28765909 0.81 LMNA (0.42) ALDH1A1LMNAALBPOLBADRA1A
SCHEMBL3611848 0.81 LMNA (0.41) ALDH1A1LMNAALBPOLBADRA1A
SCHEMBL30841853 0.81 ALDH1A1 (0.41) ALDH1A1LMNAALBPOLBADRA1A
SCHEMBL1878105 0.81 ALDH1A1 (0.43) ALDH1A1LMNAALBPOLBADRA1A
SCHEMBL27583424 0.81 ALDH1A1 (0.41) ALDH1A1LMNAALBPOLBADRA1A
SCHEMBL339966 0.81 ALDH1A1 (0.41) ALDH1A1LMNAALBPOLBADRA1A
SCHEMBL3694341 0.80 TK1 (0.43) TK1TYMPRNASE1
SCHEMBL2633815 0.80 LMNA (0.41) ALDH1A1LMNAALBPOLBADRA1A
SCHEMBL28016980 0.79 ALDH1A1 (0.40) ALDH1A1LMNAALBPOLBADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250207121-A1 METHODS FOR THE REMOVAL OF DOUBLE-AND/OR MULTI-STRANDED NUCLEIC ACID IMPURITIES FROM RNA PREPARATIONS BY LOW pH TREATMENT Sartorius BIA Separations D.O.O (SI) 2025-06-26 US disclosed
WO-2023194562-A1 METHODS FOR THE REMOVAL OF DOUBLE- AND/OR MULTI-STRANDED NUCLEIC ACID IMPURITIES FROM RNA PREPARATIONS BY LOW pH TREATMENT SARTORIUS BIA SEPARATIONS D.O.O. (SI) 2023-10-12 WO disclosed
EP-4257685-A1 METHODS FOR THE REMOVAL OF DOUBLE- AND/OR MULTI-STRANDED NUCLEIC ACID IMPURITIES FROM RNA PREPARATIONS BY LOW PH TREATMENT Sartorius BIA Separations d.o.o. (SI) 2023-10-11 EP disclosed
US-7608402-B2 DNA methylation specific signal amplification LI WEIWEI 2009-10-27 US disclosed
US-20090181373-A1 DNA methylation specific signal amplification LI WEIWEI 2009-07-16 US disclosed
CN-1780922-A Compositions and methods for the treatment of severe acute respiratory syndrome (SARS) ISIS PHARMACEUTICALS INC (US) 2006-05-31 CN disclosed