Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALB | P02768 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | TK1 | P04183 | 6/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30841853 | 1.00 | ALDH1A1 (0.41) | ALDH1A1LMNAALBBLMPOLB | |
| SCHEMBL4748323 | 0.88 | TK1 (0.35) | ALDH1A1LMNAALBBLMPOLB | |
| SCHEMBL4749295 | 0.86 | PYGM (0.39) | ALDH1A1LMNAALBBLMPOLB | |
| SCHEMBL2633815 | 0.84 | LMNA (0.41) | ALDH1A1LMNAALBBLMPOLB | |
| SCHEMBL2012504 | 0.84 | ALDH1A1 (0.43) | ALDH1A1LMNAALBBLMPOLB | |
| SCHEMBL28765909 | 0.84 | LMNA (0.42) | ALDH1A1LMNAALBBLMPOLB | |
| SCHEMBL8412869 | 0.83 | ALDH1A1 (0.40) | ALDH1A1LMNAALBBLMPOLB | |
| SCHEMBL1878105 | 0.82 | ALDH1A1 (0.43) | ALDH1A1LMNAALBBLMPOLB | |
| SCHEMBL3611848 | 0.82 | LMNA (0.41) | ALDH1A1LMNAALBBLMPOLB | |
| SCHEMBL27583424 | 0.82 | ALDH1A1 (0.41) | ALDH1A1LMNAALBBLMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2858681-A2 | RADIOLABELED ANALOG(S) OF COMPOUND 0118 AND USE THEREOF IN CONNECTION WITH PET AND/OR SPECT IMAGING TO DETERMINE WHETHER A PHARMACEUTICAL CONTAINING COMPOUND 0118 IS A CANDIDATE CANCER TREATMENT FOR A PATIENT | Koninklijke Philips N.V. (NL) | 2015-04-15 | — | — | EP | claimed |
| US-8980222-B2 | Diagnostic use of endothelin ETB receptor agonists and ETA receptor antagonists in tumor imaging | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2015-03-17 | — | — | US | claimed |
| WO-2013186690-A2 | RADIOLABELED ANALOG(S) OF COMPOUND 0118 AND USE THEREOF IN CONNECTION WITH PET AND/OR SPECT IMAGING TO DETERMINE WHETHER A PHARMACEUTICAL CONTAINING COMPOUND 0118 IS A CANDIDATE CANCER TREATMENT FOR A PATIENT | KONINKLIJKE PHILIPS N.V. (NL) | 2013-12-19 | — | — | WO | claimed |
| EP-2542155-A2 | CANCER DIAGNOSIS AND IMAGING | TAU Therapeutics LLC (US) | 2013-01-09 | — | — | EP | claimed |
| US-20120321561-A1 | CANCER DIAGNOSIS AND IMAGING | TAU THERAPEUTICS LLC (US) | 2012-12-20 | — | — | US | claimed |
| WO-2011109262-A2 | CANCER DIAGNOSIS AND IMAGING | TAU THERAPEUTICS LLC (US) | 2011-09-09 | — | — | WO | claimed |
| WO-2009063254-A2 | THYMIDINE KINASE ASSAY | UNIVERSITY OF ABERTAY, DUNDEE (GB) | 2009-05-22 | — | — | WO | claimed |
| US-20080260634-A1 | Diagnostic Use of Endothelin Etb Receptor Agonists and Eta Receptor Antagonists in Tumor Imaging | DONEHEW FUND LIMITED PARTNERSHIP | 2008-10-23 | — | — | US | claimed |
| EP-1909853-A2 | IMAGING PROTOCOLS | Spectrum Dynamics LLC (US) | 2008-04-16 | — | — | EP | claimed |
| WO-2008010227-A2 | IMAGING PROTOCOLS | SPECTRUM DYNAMICS LLC (US) | 2008-01-24 | — | — | WO | claimed |
| EP-1819367-A2 | USE OF ENDOTHELIN ETB RECEPTOR AGONISTS AND ETA RECEPTOR ANTAGONISTS IN TUMOR IMAGING | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2007-08-22 | — | — | EP | claimed |
| WO-2007010534-A2 | IMAGING PROTOCOLS | SPECTRUM DYNAMICS LLC (US) | 2007-01-25 | — | — | WO | claimed |
| US-7145000-B2 | Markable compounds for easy synthesis of 3'-[18F] fluoro-3'-deoxynucleotides, and method for their production | DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES OFFENTLICHEN RECHTS (DE) | 2006-12-05 | — | — | US | claimed |
| WO-2006057988-A2 | USE OF ENDOTHELIN ETB RECEPTOR AGONISTS AND ETA RECEPTOR ANTAGONISTS IN TUMOR IMAGING | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2006-06-01 | — | — | WO | claimed |
| US-20050143338-A1 | 1-(2,5'-Anhydro-lyxofuranosyl) thymines for the synthesis of radiomarked fluoro-3 deoxynucleotides | DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES OFFENTLICHEN RECHTS (DE) | 2005-06-30 | — | — | US | claimed |
| WO-1991000867-A1 | 5'-DIPHOSPHOHEXOSE NUCLEOSIDE PHARMACEUTICAL COMPOSITIONS | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 1991-01-24 | — | — | WO | claimed |
| CN-118679145-A | Biomolecule-polymer-agent conjugates for delivery of agents | 麻省理工学院 | 2024-09-20 | — | — | CN | disclosed |
| US-20240296559-A1 | SYSTEMS AND METHODS FOR CHARACTERIZING INTRA-TUMOR REGIONS ON QUANTITATIVE ULTRASOUND PARAMETRIC IMAGES TO PREDICT CANCER RESPONSE TO CHEMOTHERAPY AT PRE-TREATMENT | Sunnybrook Research Institute (CA) | 2024-09-05 | — | — | US | disclosed |
| WO-2005082894-A1 | CELL TARGETING CONJUGATES | PETER MACCALLUM CANCER INSTITUTE (AU) | 2005-09-09 | — | — | WO | disclosed |
| US-20050143338-A1 | 1-(2,5'-Anhydro-lyxofuranosyl) thymines for the synthesis of radiomarked fluoro-3 deoxynucleotides | DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES OFFENTLICHEN RECHTS (DE) | 2005-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143338-A1 | 1-(2,5'-Anhydro-lyxofuranosyl) thymines for the synthesis of radiomarked fluoro-3 deoxynucleotides | NT5C3B, OGG1, XRN2 | ALDH1A1 2884/4885LMNA 291/4885ALB 3200/4885 |
| US-20080260634-A1 | Diagnostic Use of Endothelin Etb Receptor Agonists and Eta Receptor Antagonists in Tumor Imaging | EDNRB, EDNRA, ECE1 | ALDH1A1 4623/4885LMNA 1626/4885ALB 4416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.