Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KLK3 | P07288 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2528399 | 0.79 | ALDH1A1 (0.59) | GPR35ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL4777597 | 0.79 | GPR35 (0.60) | GPR35TDP1ALDH1A1LMNAMAPT | |
| SCHEMBL7828455 | 0.79 | MAOA (0.60) | GPR35TDP1ALDH1A1MAPTMEN1 | |
| SCHEMBL4761517 | 0.78 | GPR35 (0.59) | GPR35TDP1ALDH1A1LMNAMAPT | |
| SCHEMBL27485531 | 0.78 | GPR35 (0.59) | GPR35TDP1ALDH1A1LMNAMAPT | |
| SCHEMBL4250005 | 0.78 | GPR35 (1.00) | GPR35TDP1ALDH1A1LMNA | |
| SCHEMBL7628829 | 0.77 | GPR35 (0.78) | GPR35TDP1ALDH1A1LMNAMAPT | |
| SCHEMBL4254530 | 0.76 | GPR35 (0.72) | GPR35ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL4249992 | 0.76 | GPR35 (0.67) | GPR35ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL29677981 | 0.76 | PRKDC (0.55) | GPR35ALDH1A1MAPTSMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118994079-A | Method for synthesizing chromone, 1-thiochromone and gamma-pyrone compounds | 中国科学院上海药物研究所 | 2024-11-22 | — | — | CN | disclosed |
| EP-1897873-A1 | A process for the preparation of nitrile compounds used as intermediates in the synthesis of cysteinyl leukotrienes antagonists | Dipharma Francis S.r.l. (IT) | 2008-03-12 | — | — | EP | disclosed |
| US-20080039640-A1 | PROCESS FOR THE PREPARATION OF NITRILE COMPOUNDS | DIPHARMA FRANCIS S.R.L. (IT) | 2008-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080039640-A1 | PROCESS FOR THE PREPARATION OF NITRILE COMPOUNDS | NOS1, REN, NOS2 | GPR35 3732/4885TDP1 2886/4885ALDH1A1 811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.