Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 17/20 | 0.56 |
| ▸ | ADRB3 | P13945 | 6/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2012558 | 1.00 | ADRB2 (0.56) | ADRB2ADRB3ADRB1 | |
| SCHEMBL2012553 | 1.00 | ADRB2 (0.56) | ADRB2ADRB3ADRB1 | |
| SCHEMBL2009303 | 0.91 | ADRB2 (0.44) | ADRB2ADRB3ADRB1 | |
| SCHEMBL2009306 | 0.91 | ADRB2 (0.44) | ADRB2ADRB3ADRB1 | |
| SCHEMBL2009305 | 0.91 | ADRB2 (0.44) | ADRB2ADRB3ADRB1 | |
| SCHEMBL2951423 | 0.87 | ADRB2 (0.73) | ADRB2ADRB3ADRB1 | |
| SCHEMBL2951421 | 0.87 | ADRB2 (0.73) | ADRB2ADRB3ADRB1 | |
| SCHEMBL2951419 | 0.87 | ADRB2 (0.73) | ADRB2ADRB3ADRB1 | |
| Hydrochloric Acid SCHEMBL2964130 | 0.86 | ADRB2 (0.72) | ADRB2ADRB3ADRB1 | |
| Hydrochloric Acid SCHEMBL2964133 | 0.86 | ADRB2 (0.72) | ADRB2ADRB3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7964730-B2 | Amino-substituted ethylamino β2 adrenergic receptor agonists | THERAVANCE, INC. (US) | 2011-06-21 | — | — | US | disclosed |
| US-7846973-B2 | Chemical process and new crystalline form | THERAVANCE, INC. (US) | 2010-12-07 | — | — | US | disclosed |
| US-7846973-B2 | Chemical process and new crystalline form | THERAVANCE, INC. (US) | 2010-12-07 | — | — | US | disclosed |
| US-7772434-B2 | Crystalline form of a β2 adrenergic receptor agonist | THERAVANCE, INC. (US) | 2010-08-10 | — | — | US | disclosed |
| US-7772434-B2 | Crystalline form of a β2 adrenergic receptor agonist | THERAVANCE, INC. (US) | 2010-08-10 | — | — | US | disclosed |
| US-20100125150-A1 | CRYSTALLINE FORM OF A BETA2 ADRENERGIC RECEPTOR AGONIST | THERAVANCE, INC. (US) | 2010-05-20 | — | — | US | disclosed |
| US-20100125150-A1 | CRYSTALLINE FORM OF A BETA2 ADRENERGIC RECEPTOR AGONIST | THERAVANCE, INC. (US) | 2010-05-20 | — | — | US | disclosed |
| US-20100063157-A1 | CHEMICAL PROCESS AND NEW CRYSTALLINE FORM | THERAVANCE BIOPHARMA R&D IP, LLC | 2010-03-11 | — | — | US | disclosed |
| US-20100063157-A1 | CHEMICAL PROCESS AND NEW CRYSTALLINE FORM | THERAVANCE BIOPHARMA R&D IP, LLC | 2010-03-11 | — | — | US | disclosed |
| US-7557247-B2 | Crystalline form of β2 adrenergic receptor agonist | THERAVANCE, INC. (US) | 2009-07-07 | — | — | US | disclosed |
| US-7557247-B2 | Crystalline form of β2 adrenergic receptor agonist | THERAVANCE, INC. (US) | 2009-07-07 | — | — | US | disclosed |
| US-20090111850-A1 | Amino-Substituted Ethylamino Beta2 Adrenergic Receptor Agonists | THERAVANCE BIOPHARMA R&D IP, LLC | 2009-04-30 | — | — | US | disclosed |
| EP-1687257-B1 | AMINO-SUBSTITUTED ETHYLAMINO BETA2 ADRENERGIC RECEPTOR AGONISTS | THERAVANCE INC (US) | 2009-04-15 | — | — | EP | disclosed |
| US-7399863-B2 | Amino-substituted ethylamino β2 adrenergic receptor agonists | THERAVANCE, INC. (US) | 2008-07-15 | — | — | US | disclosed |
| US-20070155990-A1 | Crystalline form of beta2 adrenergic receptor agonist | THERAVANCE BIOPHARMA R&D IP, LLC | 2007-07-05 | — | — | US | disclosed |
| US-20070155990-A1 | Crystalline form of beta2 adrenergic receptor agonist | THERAVANCE BIOPHARMA R&D IP, LLC | 2007-07-05 | — | — | US | disclosed |
| US-20050113411-A1 | Amino-substituted ethylamino beta2 adrenergic receptor agonists | THERAVANCE BIOPHARMA R&D IP, LLC | 2005-05-26 | — | — | US | disclosed |
| US-20050075271-A1 | Crystalline beta2 adrenergic receptor agonist | THERAVANCE, INC. | 2005-04-07 | — | — | US | disclosed |
| US-20040248985-A1 | Crystalline form of beta2 adrenergic receptor agonist | THERAVANCE BIOPHARMA R&D IP, LLC | 2004-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100063157-A1 | CHEMICAL PROCESS AND NEW CRYSTALLINE FORM | ADRA2C, ADRB2, AGTR2 | ADRB2 2/4885ADRB3 8/4885ADRB1 6/4885 |
| US-20090111850-A1 | Amino-Substituted Ethylamino Beta2 Adrenergic Receptor Agonists | ADRB2, ADRB1, ADRA2A | ADRB2 1/4885ADRB3 6/4885ADRB1 2/4885 |
| US-20040248985-A1 | Crystalline form of beta2 adrenergic receptor agonist | ADRB2, ADRA2C, ADRA2A | ADRB2 1/4885ADRB3 6/4885ADRB1 4/4885 |
| US-20050113411-A1 | Amino-substituted ethylamino beta2 adrenergic receptor agonists | ADRB2, ADRB1, ADRA2A | ADRB2 1/4885ADRB3 6/4885ADRB1 2/4885 |
| US-20100125150-A1 | CRYSTALLINE FORM OF A BETA2 ADRENERGIC RECEPTOR AGONIST | ADRB2, ADRA2C, ADRA2A | ADRB2 1/4885ADRB3 7/4885ADRB1 4/4885 |
| US-20070155990-A1 | Crystalline form of beta2 adrenergic receptor agonist | ADRB2, ADRA2C, ADRA2A | ADRB2 1/4885ADRB3 6/4885ADRB1 4/4885 |
| US-20050075271-A1 | Crystalline beta2 adrenergic receptor agonist | ADRB2, ADRA2C, ADRA2A | ADRB2 1/4885ADRB3 7/4885ADRB1 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.